Volume No. :   1

Issue No. :  2

Year :  2009

ISSN Print :  0975-4407

ISSN Online :  2321-5836


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Wound Healing Activity of Latex of Euphorbia nivulia Buch.-Ham. in Mice



Address:   SB Badgujar1*, RT Mahajan2 and MZ Chopda2
1Department of Biotechnology, SSBT’s, College of Engineering and Technology, Bambhori, Post Box No. 94, NH – 6, Jalgaon: 425 001, Maharashtra, India.
2Department of Zoology, Moolji Jaitha College, Jalgaon: 425 002, Maharashtra, India.
*Corresponding Author
DOI No: Not Available

ABSTRACT:
Wound healing activity of Euphorbia nivulia Buch.-Ham. (Euphorbiaceae) was evaluated using excision wound model in albino mice by applying latex topically on the area of excised wound once a day for 23 days. Plant latex significantly enhanced the rate of wound contraction and period of epithelialization, which is comparable to Soframycin. Latex of this plant significantly reduces the bleeding and whole blood clotting time. Phytochemical analysis revealed the presence of alkaloids, cynogenic glycosides, phenolics, tannins and saponins. The latex of Euphorbia nivulia possesses natural ingredients capable of arresting wound bleeding and accelerating wound healing properties which suggests healing potential to cure wound.
KEYWORDS:
Bleeding time, Euphorbia nivulia, Excision wound, Wound healing.
Cite:
SB Badgujar, RT Mahajan, MZ Chopda. Wound Healing Activity of Latex of Euphorbia nivulia Buch.-Ham. in Mice. Research J. Pharmacology and Pharmacodynamics. 2009; 1(2): 90-92.
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