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Research Journal of Pharmacology and Pharmacodynamics
ISSN: 2321-5836(Online), 0975-4407(Print)
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Recent Advancement towards Treatment of Diabetes
Ishan Panchal*, B Panigrahi and CN Patel
Department of Pharmaceutical Chemistry, Shri Sarvajanik Pharmacy College, Mehsana, India.
Diabetes is a chronic disease that occurs when the pancreas does not produce enough insulin or when the body cannot effectively use the insulin it produces. Diabetes can damage the heart, blood vessels, eyes, kidneys, and nerves. In 2030, the figure of diabetic patients is expected to rise to 366 million. Diabetes is the fourth leading cause of global death by disease. Each year diabetes accounts for 3.8 million deaths. This article deals with recent advancement to wards treatment of diabetes. First it reviews emerging targets for diabetes like PTP-1B inhibitors, GSK-3 inhibitors and DPP-4 inhibitors. Second it describes recent nanotechnology research in the detection of insulin and blood sugar by implantable sensor and microphysiometer. In addition latest stem cell research occurs in diabetes treatment. At last this article give idea about working of insulin pump, glossary of pump and how pump can reduce the risk of complication of diabetes.
diabetes, PTP-1B inhibitors, GSK-3 inhibitors, DPP-4 inhibitors, nanotechnology, insulin pump, stem cell
Ishan Panchal, B Panigrahi, CN Patel. Recent Advancement towards Treatment of Diabetes. Research J. Pharmacology and Pharmacodynamics. 2010; 2(1):12-22.
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