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Research Journal of Pharmacology and Pharmacodynamics
ISSN: 2321-5836(Online), 0975-4407(Print)
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Anthelmintic and Anti-Insect Activities of Memecylon umbellatum Burm Root Extracts
SG Killedar* and HN More
Department of Pharmacognosy, Bharati Vidyapeeth College of Pharmacy, Kolhapur, M. S., India.
Different extracts of Memecylon umbellatum Burm root were screened for Anthelmintic and anti-insect activities using Indian earthworms (Pheretima posthuma) and red flour beetle, Tribolium castaneum (Herbst) respectively. The acetone and methanolic extracts exhibited significant (p<0.01) anthelmintic and anti-insect activities compared with the control and other extracts. Albendazole and Piperazine citrate were used as standards for anthelmintic activity while Neem Extract, Celphos (Aluminium phosphide) and citronellal for anti-insect activity. Chloroform, ethyl acetate and aqueous extracts showed weak activities. Acetone root extract showed most promising Anthelmintic activity at 20mg/mi compare to albendazole and insecticidal activity at 10mg concentration comparable to standard celphos (5%). Further investigations are however necessary to explore mechanism(s) of action involved in these pharmacological activities and constituents responsible for both the activities.
Memecylon umbellatum, Anthelmintic, anti-insect, Pheretima posthuma, Tribolium castaneum.
SG Killedar, HN More. Anthelmintic and Anti-Insect Activities of Memecylon umbellatum Burm Root Extracts. Research J. Pharmacology and Pharmacodynamics. 2010; 2(1):52-56.
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