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Research Journal of Pharmacology and Pharmacodynamics
ISSN: 2321-5836(Online), 0975-4407(Print)
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Gastroesophageal Reflux Disease: Pathophysiology and Treatments Available
Pankaj Rakha1*, Raj Kumar1, Supriya1, Nidhi1, Manju Nagpal2 and Gitika Arora3
1Rajendra Institute of Technology and Sciences, Sirsa (Haryana)
2Chitkara School of Pharmaceutical Sciences, Chitkara University, Barotiwala (HP)
3NCRD’s Sterling Institute of Pharmacy, Navi Mumbai.
Gastroesophageal reflux disease (GERD) is primarily a motility disorder. Escape of gastric contents into the esophagus occurs as a consequence of an incompetent gastroesophageal barrier. This barrier is weakened in the presence of an abnormally functioning Lower Esophageal Sphincter (LES). This review is focused on the epidemiology, pathophysiology and treatments of gastro-oesophageal reflux disease.
Reflux, proton pump inhibitors, H2 receptor antagonists, radiofrequency.
Pankaj Rakha, Raj Kumar, Supriya, Nidhi, Manju Nagpal , Gitika Arora. Gastroesophageal Reflux Disease: Pathophysiology and Treatments Available. Research J. Pharmacology and Pharmacodynamics. 2010; 2(2):160-164.
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