Volume No. :   3

Issue No. :  1

Year :  2011

ISSN Print :  0975-4407

ISSN Online :  2321-5836


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Hepatoprotective Effect of Pergularia daemia on Cadmium Chloride Induced Toxicity in Rats



Address:   P. Vinoth Kumar1*, Ch. Sudheer Kumar2, V. Veera Thamarai Selvi1 and A. Amala Bricey3
1Department of Biotechnology, J.J college of Arts and Science, Pudukottai, India.
2School of Life Sciences, Department of Biotechnology, University College of Engineering, JNTU, Kakinada, Andhra Pradesh, India.
3Department of Biotechnology, Bharathidasan University, Trichy, India.
*Corresponding Author
DOI No: Not Available

ABSTRACT:
The present study was undertaken to examine the inhibitory effect of the Pergularia daemia on cadmium chloride induced hepatoprotective activity in liver. In rats injected with cadmium chloride, the activities of aspartate aminotransferase (AST), alanine aminotransferase (ALT), lactate dehydrogenase (LDH), ? - glutamyl transferase (GGT) was significantly (p < 0.05) increased when compared to those values in control rats. The rats administrated with P.daemia extract and cadmium chloride showed a significantly (p < 0.05) decreased levels of serum AST, ALP, LDH and GGT. This study suggested that P.daemia may be implicated as a hepatoprotective agent for therapeutic purposes.
KEYWORDS:
Cadmium chloride, Hepatoprotective activity, Pergularia daemia.
Cite:
P Vinoth Kumar, Ch Sudheer Kumar, V Veera Thamarai Selvi , A Amala Bricey. Hepatoprotective Effect of Pergularia daemia on Cadmium Chloride Induced Toxicity in Rats.Research J. Pharmacology and Pharmacodynamics. 2011; 3(1): 19-21.
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