Volume No. :   3

Issue No. :  3

Year :  2011

ISSN Print :  0975-4407

ISSN Online :  2321-5836


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Pharmacological Evaluation of Antiasthmatic Activity of Tamarindus indica Seed



Address:   R. Suresh*, Ganesh Pandhari Mhaske, Nehru Sai Suresh Chalichem, Ashok Kumar Javvadi, Benito Johnson. D. and R. Venkatanarayanan
Department of Pharmacology, R.V.S. College Pharmaceutical Science, Sulur, Coimbatore-641 402
*Corresponding Author
DOI No: Not Available

ABSTRACT:
Practical experience and several modern research studies have shown that therapy using plant is better than using synthetic chemicals. According to ayurvedic folklore the Tamarindus indica Linn was mentioned for several ailments including asthma (kirtikar et al; 2001) the present study was planned to know the anti asthmatic activity of methanolic extract of this plant at different stages or different types of asthma using various evaluation models like, isolated goat tracheal chain preparation, bronchial hyperactivity, clonidine induced catalepsy in guinea pig, mast cell degranulation, milk induced leucocytosis in mice, milk induced eosinophilia in mice, passive paw anaphylaxis, and its activities such as bronchodilating, antihistaminic, anti inflammatory , anti allergic, mast cell stabilizing and adaptogenic activities were confirmed presenting the scope of plant for further studies. The data was analyzed by student‘t’ test or one way ANOVA followed by Dunnett test. P = 0.05 was considered as significant.
KEYWORDS:
Tamarindus indica Linn., catalepsy, leukocytosis, anaphylaxis, degranulation.
Cite:
R. Suresh, Ganesh Pandhari Mhaske, Nehru Sai Suresh Chalichem, Ashok Kumar Javvadi, Benito Johnson D, R Venkatanarayanan. Pharmacological Evaluation of Antiasthmatic Activity of Tamarindus indica Seed. Research J. Pharmacology and Pharmacodynamics. 2011; 3(3): 115-122
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