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Research Journal of Pharmacology and Pharmacodynamics
ISSN: 2321-5836(Online), 0975-4407(Print)
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Anti-Inflammatory Effect of the Embelia tsjeriam -Cottam Fruit Extracts.
Sambrekar Sudhir N
Suhas A Patil.
Sambrekar Sudhir N.1* Patil P.A.2 and Suhas A. Patil1
1Dept of Pharmacology, Maratha Mandal’s College of Pharmacy, Belgaum, India.
2Dept of Pharmacology, K.L.E’s Institute of Dental Sciences Bangalore.India.
Extracts of Embelia tsjeriam-cottam Fruits were investigated for anti-inflammatory activity with acute and chronic models. In the doses of 200 mg kg-1exhibited significant (P < 0.001) anti-inflammatory activity in all the models tested. The alcohol extract of Embelia tsjeriam-cottam at 200 mg kg-1 showed maximum inhibition of paw volume 1.21 ± 0.1 in carrageenan-induced rat paw edema while the standard drug Diclofenac it was 1.18 ± 0.1 after 6 hrs of carrageenan injection. In the chronic inflammatory model alcoholic extract inhibited the granuloma weight by 35.50 %, whereas the Diclofenac inhibited 46.18%.
Anti-inflammatory activity, carrageenan induced rat paw, cotton pellet induced granuloma, Embelia tsjeriam-cottam
Sambrekar Sudhir N, Patil PA, Suhas A Patil. Anti-Inflammatory Effect of the Embelia tsjeriam -Cottam Fruit Extracts. Research J. Pharmacology and Pharmacodynamics. 2011; 3(5): 246-249.
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