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Research Journal of Pharmacology and Pharmacodynamics
ISSN: 2321-5836(Online), 0975-4407(Print)
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Diuretic and laxative activity of ethanolic extract of Mollugo pentaphylla Linn.
HK Sundeep Kumar.
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S.K. Sahu1*, D. Das2, N.K. Tripathy1 and H.K. Sundeep Kumar1
1School of Pharmaceutical Science & Research, Berhampur University, Berhampur, Odisha –760007
2School of Pharmaceutical Sciences, SOA University, Bhubaneswar, Odisha-754030
Crude ethanolic extract of Mollugo pentaphylla Linn. (family- Aizoaceae) was investigated for diuretic and laxative activity in albino rats at 200 and 400 mg/kg p.o. Which was compared with standard drugs Furosemide (10mg/kg, p.o.) and Agar agar (300mg/kg, p.o.) respectively. The extract was found to produce significant diuretic as well as laxative activity at dose 400 mg/kg. The plant was also found to possess the phytoconstituents like carbohydrates, alkaloids, gums, saponins, flavanoids, tanins and steroids.
Mollugo pentaphylla; Acute toxicity study; Diuretic activity; Laxative activity
SK Sahu, D Das, NK Tripathy , HK Sundeep Kumar. Diuretic and laxative activity of ethanolic extract of Mollugo pentaphylla Linn. Research J. Pharmacology and Pharmacodynamics. 2012; 4(5): 278-280.
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