Volume No. :   4

Issue No. :  5

Year :  2012

ISSN Print :  0975-4407

ISSN Online :  2321-5836


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Evaluation of anti-obesity activity of Lantana camara var Linn on butter induced Hyperlipidemia in Rats



Address:   Rohit Gundamaraju1*, Diana Vivian Atigari1, Mrs. D. S. Helen Sheeba1, Dr. Ramesh C.2
1Department of Pharmacology, Malla Reddy Institute of Pharmaceutical Sciences, Maisammaguda, Dhulapally (Post via Hakimpet), Secunderabad (500014) AP, India.
2GSN Pharmaceuticals Pvt. Ltd., Rajeev Gandhi Nagar, Kukatpally, Hyderabad (500072), AP, India.
*Corresponding Author
DOI No: Not Available

ABSTRACT:
The hypolipidemic activity of Lantana camara was studied on high fat diet induced models of hyperlipedemia in rats. Hyper lipidemia condition established by butter was evidenced by enhancement in levels of cholesterol, tri-glycerides, LDL, VLDL. Methanolic extract showed significant hypolipidemic effect by lowering of serum levels of serum cholesterol, TG, LDL, VLDL and increased dl level. Ethanobotanical knowledge of medicinal plants is some of the most prominent source of new drugs and has shown potential results for treatment of obesity. Prelimnary phytochemical analysis revealed thye presence of phyto constituents such as steroids, flavinoids, alkaloids.
KEYWORDS:
High fat diet, Lantana camara, obesity.
Cite:
Rohit Gundamaraju Diana Vivian Atigari, DS Helen Sheeba, Ramesh C. Evaluation of anti-obesity activity of Lantana camara var Linn on butter induced Hyperlipidemia in Rats. Research J. Pharmacology and Pharmacodynamics. 2012; 4(5): 315-318.
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