Volume No. :   5

Issue No. :  6

Year :  2013

ISSN Print :  0975-4407

ISSN Online :  2321-5836


Registration

Allready Registrered
Click to Login

Antihyperlipidemic Activity of Paspalum scrobiculatum L. Grains Extract in Albino Rats.



Address:   Satish Narra*, Bandenawaz Ramadurg, Saraswathi C.D
Department of Pharmacology, Gautham College of Pharmacy, Bangalore, Karnataka, India.
*Corresponding Author
DOI No: Not Available

ABSTRACT:
Pasapalum scrobiculatum also named kodo millet is cultivated as an annual. It has been cultivated for 3000 years in India, where it is considered as a minor cereal crop except in the Deccan. The grains are used as human food: ground into meal and used as puddings. There are some reports that Paspalum scrobiculatum is used traditionally anti-hyperlipidemic plant, but there is no scientific anti-hyperlipidemic activity has been carried out by this plant in rats. The model used to evaluate the anti hyperlipidemic activity were high fat diet induced hyperlipidemic rats, physical parameters like body weights, feed intake, organ weights, biochemical parameters like blood glucose, lipid profile were monitored were monitored. In high fat diet (HFD) induced hyperlipidemia rats treated with HAPS 600mg/kg, 400mg/kg, 200mg/kg, b.w. p.o (respectively) showed significant decrease in body weights, TG, TC, LDL, VlDL and significant increase in HDL compared to HFD control rats.
KEYWORDS:
HFD, HAPS, Paspalum scrobiculatum, anti-hyperlipidemic activity and hyperlipidemia.
Cite:
Satish Narra, Bandenawaz Ramadurg, Saraswathi CD. Antihyperlipidemic Activity of Paspalum scrobiculatum L. Grains Extract in Albino Rats. Research J. Pharmacology and Pharmacodynamics. 2013; 5(6): 362-370 .
[View HTML]      [View PDF]



Visitor's No. :   124376