Volume No. :   6

Issue No. :  1

Year :  2014

ISSN Print :  0975-4407

ISSN Online :  2321-5836


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Anti-obesity Activities of Hydro-Alcoholic Extract of Echinochloa crusgalli (L.) P. Beauv Grains in Albino Rats



Address:   Maradani Pavani*, Bandenawaz Ramadurg and Varshitha C.
Department of Pharmacology, Gautham College of Pharmacy, Bangalore Karnataka
*Corresponding Author
DOI No: Not Available

ABSTRACT:
Obesity is often defined simply as a condition of abnormal or excessive fat accumulation in adipose tissue, to the extent that health may be impaired. The present study was undertaken to evaluate anti-obesity effect of hydro-alcoholic extracts of Echinochloa crusgalli on high fat diet induced obesity in albino rats. Obesity was induced by administration of high fat diet for 4 weeks with normal diet and obtained obese rats were treated with Echinochloa crusgalli in a dose of 200, 400 and 600 mg/kg, b.w. p.o for next 4 weeks. It showed significant decrease in body weights, adipose tissue weight, SGOT and SGPT levels, blood glucose levels, LDL-C, VLDL-C, total cholesterol, triglyceride levels, atherogenic index, and also showed significantincrease in HDL-C levels when compared with high fat diet control.
KEYWORDS:
Obesity, Echinochloa crusgalli, high fat diet, body weight, adipose tissue weight, lipid profile, atherogenic index, serum blood glucose levels
Cite:
Maradani Pavani, Bandenawaz Ramadurg, Varshitha C. Anti-obesity Activities of Hydro-Alcoholic Extract of Echinochloa crusgalli (L.) P. Beauv Grains in Albino Rats. Research Journal of Pharmacology and Pharmacodynamics. 2014; 6(1): 13-20.
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