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Research Journal of Pharmacology and Pharmacodynamics
ISSN: 2321-5836(Online), 0975-4407(Print)
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Hepatoprotective Activity of Stem Bark of Nyctanthes arbor-tristis linn
Manmeet Singh Saluja.
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Vaibhav Tripathi1*, Adeep Kujur2 , Dr. Manmeet Singh Saluja3
1Columbia College of Pharmacy, Raipur-493111 C.G. India
2University Institute of Pharmacy, Pt. Ravishankar Shukla University, Raipur-492010 C.G. India
3 TIT College of Pharmacy, Bhopal-462001 M.P. India
The present study is to evaluate the hepatoprotective effects of the 50% hydro-ethanol (Heena) extracts of stem bark of Nyctanthes arbor-tristis linn, against paracetamol induced hepatotoxicity in rats. The hepatoprotective effects of HEENA (500 mg/kg) was estimated by liver function test and serum profile. The results revealed that the extract of selected plant produce significant hepatoprotective effect not only by decreasing serum transaminase (SGPT and SGOT), alkaline phosphate and total bilirubin, but also significantly increased the levels of serum proteins (albumin, fibrinogen haeptoglobin, ceruloplasin, transferring etc). The effects of Heena was comparable with standard drug silymarin.
Hepatotoxicity; Nyctanthes arbor-tristis linn; Heena; SGPT; SGOT.
Vaibhav Tripathi, Adeep Kujur, Manmeet Singh Saluja. Hepatoprotective Activity of Stem Bark of Nyctanthes arbor-tristis linn. Research Journal of Pharmacology and Pharmacodynamics. 2015; 7(3): 124-128.
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