Volume No. :   7

Issue No. :  3

Year :  2015

ISSN Print :  0975-4407

ISSN Online :  2321-5836


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Evaluation of Anti-diabetic and Anti-inflammatory activities of ethanolic extract of whole plant of Inula racemosa



Address:   Sanu G. Sam1*, Anjan Kumar1, Veeresh Babu. D1, Narayana Swamy V.B2
1Department of Pharmacology, Karavali College of Pharmacy, Mangalore.
2Department of Pharmacognosy, Karavali College of Pharmacy, Mangalore
*Corresponding Author
DOI No: 10.5958/2321-5836.2015.00024.5

ABSTRACT:
The present study was designed to evaluate the antidiabetic and anti-inflammatory activity of ethanolic extract of whole plant of Inula racemosa using different animal models. Antidiabetic activity was evaluated by using various two animal models. The alloxan induced diabetes method and streptozocin induced diabetes method along with biochemical parameters like SALP, SGPT, SGOT, Triglycerides, Total proteins were employed to investigate antidiabetic potential of Inula racemosa. Anti-inflammatory activity was evaluated using formalin induced paw edema model and croton oil ear edema model. Carrageenan induced paw edema model uses change in paw volume of control, test, and standard respectively to find out percentage inhibition of edema. The study revealed that the whole plant of Inula racemosa possess a significant anti-diabetic and anti-inflammatory activity.
KEYWORDS:
Inula racemosa, alloxan induced diabetes method, Streptozocin induced diabetes method, formalin induced paw edema model, croton oil ear edema model.
Cite:
Sanu G Sam, Anjan Kumar, Veeresh Babu D, Narayana Swamy VB. Evaluation of Anti-diabetic and Anti-inflammatory activities of ethanolic extract of whole plant of Inula racemosa. Research Journal of Pharmacology and Pharmacodynamics. 2015; 7(3): 129-134.
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