Author(s): Mansuri Sajid, Goswami Raksha, Jain Neetesh Kumar

Email(s): sidkhan1593@gmail.com , rakshag23@gmail.com

DOI: 10.52711/2321-5836.2021.00007   

Address: Mansuri Sajid*, Goswami Raksha, Jain Neetesh Kumar
Department of Pharmacology, Faculty of Pharmacy, Oriental University, Indore, M.P.
*Corresponding Author

Published In:   Volume - 13,      Issue - 2,     Year - 2021


ABSTRACT:
Coordinated investigation of characteristic antidiabetic specialists with attendant disposal of poisonous impacts is the objective in diabetes treatment. The clinical result of foundational treatment lies on controlled oral hypoglycemic specialists by assessing the administrative impact on amylase and glucosidase movement and doing generally less unfriendly impact to the patient. Diabetes mellitus is a shocking problem and prompts different other metabolic issue. It is assessed that yearly occurrence rate will keep on expanding later on around the world. Diabetes includes with the advancement of miniature and full scale vascular diabetic difficulties. In people glucose resistance impedes preceding development beginning of hyperglycemia and is generally utilized as a clinical file to anticipate the possibility of creating diabetes. The goal of our examination is to research the hypoglycemic impacts in the fluid concentrates of okra seed and strip. Glucosidase are a gathering of stomach related catalysts which separate the dietary starches into straightforward monosaccharide. Glucosidase inhibitors, for example, acarbose lessen the pace of sugar assimilation and defer the starch ingestion from the stomach related lot. Accordingly, they can possibly forestall the improvement of type II diabetes mellitus by bringing down the after supper glucose levels. In monosaccharide glucose can be promptly assimilated from the gastrointestinal plot into the circulation system after the hydrolysis of glycosidic securities in absorbable sugar nourishments containing starch by the protein alpha amylase. Hindrance of these catalysts diminished the high post prandial blood glucose tops in diabetics. In this investigation, alpha amylase hindrance In-Vitro model was utilized to screen.


Cite this article:
Mansuri Sajid, Goswami Raksha, Jain Neetesh Kumar. In vitro Alpha glucosidase and Aldolase reductase Inhibitory activity of Holoptelea integrifolia. Research Journal of Pharmacology and Pharmacodynamics. 2021; 13(2):35-0. doi: 10.52711/2321-5836.2021.00007

Cite(Electronic):
Mansuri Sajid, Goswami Raksha, Jain Neetesh Kumar. In vitro Alpha glucosidase and Aldolase reductase Inhibitory activity of Holoptelea integrifolia. Research Journal of Pharmacology and Pharmacodynamics. 2021; 13(2):35-0. doi: 10.52711/2321-5836.2021.00007   Available on: https://rjppd.org/AbstractView.aspx?PID=2021-13-2-1


REFERENCES:
1.    Khan a., Zaman G., Anderson R.A, J clinbiochem nutr, (2009), 44: 52-56.
2.    International diabetes federation, Brussels, http://www. diabetesatlas.org/Retrievedon (July 2010).
3.    Das AK. Rai, A world without diabetes and its complications: A preventive program. In: Jayaram BM (Ed.), type 2 diabetes and its complications; A preventive program, microlabe limited: Banglore (2008) 1-2.
4.    Cambon- Thomsen A.; Rial-Sebbag E.; Knoppers B.M.; “Trends in ethical and legal frameworks for the use of human biobanks”. European Respiratory Journal (2007); 30 (2): 373-382.
5.    Cooke DW, Plotnick L.; “Type 1 Diabetes Mellitus in Pediatrics”. Pediatr Rev (2008); 29 (11): 374-84; quiz 385. doi: 10.1542/pir.29-11-374., PMID 18977856.
6.    Kazemipoor M, Radzi CW, Cordell GA, Yaze I. Safety, efficacy and metabolism of traditional medicinal plants in the management of obesity: A Review. Int J Chem Eng Appl (2012);3(4): 288-292.
7.    Mahmud, S., H.M. Shareef, S. Ahmad, G.H. Gouhar Rizwani, Pharmacognostic studies on freshleaves of Holoptelea integrifolia (Roxb.). Pakistan Journal of Botany, (2010); 42: 3705-708.
8.    Mathur S, Sen S, Ramesh L, Satish Kumar M. Utilization pattern of antiepileptic drugs and their adverse effects in a teaching hospital. Asian J Pharm Clin Res. (2010); 3: 55–59.
9.    Kalaiselvan V, Kalpeshkumar SA, Patel FB, Shah CN et al: Quality assessment of different marketed brands of Dasamoolaristam, an Ayurvedic formulation. Int. J of Ayurveda Res. (2010); 1(1): 10‐13.
10.    World Population Datasheet. (2016) Population Reference Bureau.
11.    Vinod, NV, Haridas, M, Sadasivan, C. Isolation of 1, 4- naphthalenedione, an antibacterial principle from the leaves of Holoptelea integrifolia and its activity against β-lactam resistant Staphylococcus aureus. Indian Journal of Biochemistry and Biophysics (2010); 47: 53-55.
12.    Sriwastava NK, Shreedhara CS, Aswatha Ram HN: Standardization of Ajmodadi churna, a polyherbal formulation. J Pharmacog Res, (2010); 2(2): 98‐101.
13.    Singh, M., S. Khatoon, S. Singh, V. Kumar, A.K.S. Rawat and S. Mehrotra, Antimicrobial screening of ethnobotanically important stem bark of medicinal plants. Pharmacognosy Research, (2010); 2: 254-57.
14.    Philomena G. Concerns regarding the safety and toxicity of medicinal plants - An overview. J Appl Pharmaceut Sci (2011); 01(6): 40-44.
15.    Nadella, D. and P.M. Paarakh, Antibacterial activity of different extracts of Holoptelea integrifolia (Roxb.) Planch. International Research Journal of Pharmacy, (2011);2: 111-113.
16.    Lakshmi, K.S., S.S. Sharma, T. Rajesh and V. Chitra, Antitumour activity of Holoptelia integrifolia on Dalton. S ascetic lymphoma in Swiss albino mice. International Journal of Green Pharmacy, (2010); 4: 44-47.

Recomonded Articles:

Author(s): Syed Sagheer Ahmed, Chandra Prakash. K, Saba Tabassum, Noor Salma, Ahalya Devi. K H

DOI: 10.5958/2321-5836.2019.00003.X         Access: Open Access Read More

Author(s): Aswani P. S., Kshirod Kumar Ratha, Dighe Dattatray Pandurang, M. M. Rao, Remya Vijayan

DOI: 10.5958/2321-5836.2018.00008.3         Access: Open Access Read More

Author(s): Sudhanshu Kumar Meher, Banmali Das, Purnendu Panda, GC Bhuyan, MM Rao.

DOI: 10.5958/2321-5836.2016.00006.9         Access: Open Access Read More

Author(s): Purnendu Panda, Banamali Das, DS Sahu, SK Meher, BK Das, MM Rao, GChD Naga Lakshmi.

DOI: 10.5958/2321-5836.2015.00011.7         Access: Open Access Read More

Author(s): Purnendu Panda, Banamali Das, DS Sahu, SK Meher, Das, GC Nanda.

DOI: Not Available         Access: Open Access Read More

Author(s): Nikhil P. Varghese, Shekshavali T. , Prathib B., I.J. Kuppast

DOI: 10.5958/2321-5836.2017.00007.6         Access: Open Access Read More

Author(s): Syed Shafeeq. R, Shekshavali. T, Syed Sulthan Ahamed. S N

DOI: 10.5958/2321-5836.2018.00026.5         Access: Open Access Read More

Author(s): M Lavanya, Asish Bhaumik, A Gopi Reddy, Ch Manasa, B Kalyani, S Sushmitha

DOI: 10.5958/2321-5836.2016.00012.4         Access: Open Access Read More

Author(s): Nadiminti Satish Reddy, Vidyasabbani, B. Pravanthi, B. Vijaya Laxmi, B. Harika.

DOI: 10.5958/2321-5836.2016.00023.9         Access: Open Access Read More

Author(s): Madhavi Sahu, S. Prakash Rao

DOI: 10.5958/2321-5836.2018.00031.9         Access: Open Access Read More

Author(s): Syed Sulthan Ahamed S N, Shekshavali. T, Syed Shafeeq. R

DOI: 10.5958/2321-5836.2018.00015.0         Access: Open Access Read More

Author(s): Srinibash Sahoo, AK Das, Kamadev Das.

DOI: 10.5958/2321-5836.2015.00039.7         Access: Open Access Read More

Author(s): Prathib B, Nikhil P Varghese, Virupaksha J. H, Kuppast I. J.

DOI: 10.5958/2321-5836.2017.00006.4         Access: Open Access Read More

Author(s): Indrayani D. Raut, Akshada N. Kakade , Jadhav Snehal, Jadhav Priyanka, Kabir Amruta

DOI: 10.5958/2321-5836.2017.00002.7         Access: Open Access Read More

Author(s): Jayanth P. C. , Prasanna Kumar Kar, M. Niranjan Babu

DOI: 10.5958/2321-5836.2016.00020.3         Access: Open Access Read More

Author(s): Subbiah Murugesan, Sundaresan Bhuvaneswari, U.S. Mahadeva Rao, Vajiravelu Sivamurugan

DOI: 10.5958/2321-5836.2017.00022.2         Access: Open Access Read More

Author(s): Mohammed Haleel P M , Rashid K, C. Senthil Kumar

DOI: 10.5958/2321-5836.2018.00005.8         Access: Open Access Read More

Author(s): Khushbu Chauhan, Payal Santwani, Lalkrushn Parmar, Roshni Solanki. Subodh Adeshara.

DOI: Not Available         Access: Open Access Read More

Author(s): D. Benito Johnson, Faisal N.V, Rashid. K, Mohammed Haleel, V. Venkatanarayanan

DOI: 10.5958/2321-5836.2016.00018.5         Access: Open Access Read More

Author(s): Purnendu Panda, Banamali Das, DS Sahu, SK Meher, Bikartana Das, GC Bhuyan, Abhijit Joshi MM Rao.

DOI: 10.5958/2321-5836.2015.00027.0         Access: Open Access Read More

Research Journal of Pharmacology and Pharmacodynamics (RJPPD) is an international, peer-reviewed journal....... Read more >>>

RNI: Not Available                     
DOI: 10.5958 2321-5836 


Recent Articles




Tags