Sterilization, which is any process, physical or chemical, that destroys all forms of life, it is used especially to destroy microorganisms, spores, and viruses. Precisely defined, sterilization is the complete destruction of all microorganisms by a suitable chemical agent or by heat, either wet steam. In this review, we discussed about various suitable techniques that used for removing of infectious agents. The heat sterilization can be applied only to the thermostable products, and chemical sterilization is also used for any types of plastic or glass materials that degrade with heat. The Gas sterilization involves exposing equipment to chemical gases in an enclosed heated or pressurized chamber.
Cite this article:
Ravi Kumar, Atul Rana. Basic Concepts of Sterilization Techniques. Research Journal of Pharmacology and Pharmacodynamics. 2021;13(4):155-1. doi: 10.52711/2321-5836.2021.00029
Ravi Kumar, Atul Rana. Basic Concepts of Sterilization Techniques. Research Journal of Pharmacology and Pharmacodynamics. 2021;13(4):155-1. doi: 10.52711/2321-5836.2021.00029 Available on: https://rjppd.org/AbstractView.aspx?PID=2021-13-4-8
1. Rutala WA, APIC Guidelines Committee. APIC guideline for selection and use of disinfectants. Am J Infect Control 1996; 24:313-42.
2. Rutala WA, Weber DJ. Disinfection of endoscopes: review of new chemical sterilants used for high-level disinfection. Infect Control Hosp Epidemiol 1999; 20:69-76.
3. Advanced Sterilization Products, Johnson & Johnson. Cidex OPA high level disinfection solution: technical information. Irvine (CA): Advanced Sterilization Products; 1999.
4. Gregory AW, Schaalje B, Smart JD, Robison RA. The mycobactericidal efficacy of ortho-phthalaldehyde and the comparative resistances of Mycobacterium bovis, Mycobacterium terrae, and Mycobacterium chelonae. Infect Control Hosp Epidemiol 1999:20:324-30.
5. Walsh SE, Maillard JY, Russell AD. Ortho-phthalaldehyde: a possible alternative to glutaraldehyde for high level disinfection. J Appl Microbiol 1999; 86:1039-46.
6. Alfa MJ, Sitter DL. In-hospital evaluation of ortho-phthalaldehyde as a high level disinfectant for flexible endoscopes. J Hosp Infect 1994; 26:15-26.
7. Chen X. A comparison of the useful life of Cidex activated dialdehyde solution and Cidex OPA in AER system. Irvine (CA): Advanced Sterilization Products; 1999.
8. Weber DJ, Rutala WA. Role of environmental contamination in the transmission of vancomycin-resistant enterococci. Infect Control Hosp Epidemiol 1997; 18:306-9.
9. Rutala WA, Stiegel MM, Sarubbi FA, Weber DJ. Susceptibility of antibiotic-susceptible and antibiotic-resistant hospital bacteria to disinfectants. Infect Control Hosp Epidemiol 1997; 18:417-21.
10. Anderson RL, Carr JH, Bond WW, Favero MS. Susceptibility of vancomycin-resistant enterococci to environmental disinfectants. Infect Control Hosp Epidemiol 1997; 18:195-9.
11. Rutala WA, Gergen MF, Weber DJ. Evaluation of a new surface germicide (SurfacineTM) with antimicrobial persistence. Infect Control Hosp Epidemiol 2000; 21:103.
12. Fraise AP. Choosing disinfectants. J Hosp Infect 1999;43:255-64.
13. Tanaka H, Hirakata Y, Kaku M, Yoshida R, Takemura H, Mizukane R. Antimicrobial activity of superoxidized water. J Hosp Infect 1996; 34:43-9.
14. Selkon JB, Babb JR, Morris R. Evaluation of the antimicrobial activity of a new super-oxidized water, Sterilox, for the disinfection of endoscopes. J Hosp Infect 1999; 41:59-70.
15. Shetty N, Srinivasan S, Holton J, Ridgway GL. Evaluation of microbicidal activity of a new disinfectant: Sterilox 2500 against Clostridium difficile spores, Helicobacter pylori, vancomycin resistant Enterococcus species, Candida albicans and several Mycobacterium species. J Hosp Infect 1999; 41:101-5.
16. Advanced Sterilization Products new automated endoscope reprocessing system with NSX sterilant. Technical report. Irvine (CA): Advanced Sterilization Products; 2000.
17. Rutala WA, Weber DJ. Clinical effectiveness of low-temperature sterilization technologies. Infect Control Hosp Epidemiol 1998; 19:798-804.
18. Rutala WA, Gergen MF, Weber DJ. Evaluation of a rapid readout biological indicator for flash sterilization with three biological indicators and three chemical indicators. Infect Control Hosp Epidemiol 1993; 14:390-4.
19. Rutala WA, Jones SM, Weber DJ. Comparison of a rapid readout biological indicator for steam sterilization with four conventional biological indicators and five chemical indicators. Infect Control Hosp Epidemiol 1996:17:423-8.
20. Rutala WA, Gergen MF, Weber DJ. Sporicidal activity of a new lowtemperature sterilization technology: the Sterrad 50 sterilizer. Infect Control Hosp Epidemiol 1999; 20:514-16.
21. Rutala WA, Gergen MF, Weber DJ. Comparative evaluation of the sporicidal activity of new low-temperature sterilization technologies: ethylene oxide, 2 plasma sterilization systems, and liquid peracetic acid. Am J Infect Control 1998; 26:393-8.
22. Zhang J, Davis TA, Matthews MA. Sterilization using high-pressure carbon dioxide. J Supercrit Fluid 2006; 38: 354–372.
23. McDonnell G, Sheard D. A practical guide to decontamination in healthcare. Oxford, UK: John Wiley & Sons, 2012.
24. Block SS. Disinfection, sterilization, and preservation. Philadelphia, PA: Lippincott Williams & Wilkins, 2001.
25. Moore MA, McIlroy BK and Phillips RE. Nonaldehyde sterilization of biologic tissue for use in implantable medical devices. ASAIO J 1997; 43: 23–30.
26. Rozema FR, Bos RRM, Boering G. The effects of different steam-sterilization programs on material properties of poly (l-lactide). J Appl Biomater 1991; 2: 23–28.
27. Yunoki S, Ikoma T, Monkawa A. Influence of gamma irradiation on the mechanical strength and in vitro biodegradation of porous hydroxyapatite/collagen composite. J Am Ceram Soc 2006; 89: 2977–2979.
28. Cottam E, Hukins DW, Lee K. Effect of sterilisation by gamma irradiation on the ability of polycaprolactone (PCL) to act as a scaffold material. Med Eng Phys 2008; 31: 221–226.
29. Hooper KA, Cox JD, Kohn J. Comparison of the effect of ethylene oxide and gamma-irradiation on selected tyrosine-derived polycarbonates and poly (L-lactic acid). J Appl Polym Sci 1997; 63: 1499–1510.
30. Bertoldi S, Farè S, Haugen HJ. Exploiting novel sterilization techniques for porous polyurethane scaffolds. J Mater Sci: Mater M 2015; 26: 1–12.
31. Shearer H, Ellis MJ, Perera SP. Effects of common sterilization methods on the structure and properties of poly (D, L lactic-co-glycolic acid) scaffolds. Tissue Eng 2006; 12: 2717–2727.