Sangeetha Shankar, P. Gopinath, E. Roja
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Sangeetha Shankar1, P. Gopinath2, E. Roja3
1Graduate Student, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences (SIMATS), Saveetha University, Chennai.
2Assistant Professor, Department of Microbiology, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences (SIMATS), Saveetha University, Chennai.
3Tutor, Department of Public Health Dentistry, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences (SIMATS), Saveetha University, Chennai.
Volume - 14,
Issue - 1,
Year - 2022
Herbs and spices are not just useful to us as flavouring agents but they are actually nature's way to treat dental infections also. Several dental problems like tooth ache, caries, etc have become very common among the human population across the globe. These are mainly due to the action of microorganisms like Streptococcus mutans, Streptococcus sobrinus, lactobacilli, etc. Such problems can actually be cured naturally by using herbs and spices like cloves, thyme, peppermint leaves, goldenseal, green tea, etc which contain particular substances (that are found in dental medicines), which act against the microorganisms causing dental problems by either killing them or inhibiting their growth, are used to treat these problems. Apart from the above use, it is also effective in cases of infections where allopathic medications have no or minimal actions which may be due to the increased resistance exhibited by the pathogens to particular allopathic medications, some antibacterial agents currently used in dentistry produces adverse-affects like nausea, vomiting, diarrhoea, headache, staining of teeth, etc. and financial considerations in relation to allopathic medications in developing countries creates a need for alternative prevention and treatment options that are safe, effective and economical. Hence, the search for alternative products continues and herbs and spices that were used as traditional medicines in the ancient times are considered as good alternatives. Therefore, understanding the role of herbs and spices in controlling dental infection scan help people to cure and prevent these infections in a natural way and help them overcome all the above problems.
Cite this article:
Sangeetha Shankar, P. Gopinath, E. Roja. Role of Spices and Herbs in Controlling Dental Problems. Research Journal of Pharmacology and Pharmacodynamics.2022;14(1):23-8. doi: 10.52711/2321-5836.2022.00004
Sangeetha Shankar, P. Gopinath, E. Roja. Role of Spices and Herbs in Controlling Dental Problems. Research Journal of Pharmacology and Pharmacodynamics.2022;14(1):23-8. doi: 10.52711/2321-5836.2022.00004 Available on: https://rjppd.org/AbstractView.aspx?PID=2022-14-1-4
1. Savage, Amir; Eaton, Kenneth A.; Moles, David R.; Needleman, Ian ". A systematic review of definitions of periodontitis and methods that have been used to identify this disease". Journal of Clinical Periodontology 2009; 36 (6): 458–467.
2. Jyotsna Srinath, Lakshmi. T. Application of spices in dentistry- A Literature Review Available at URL: http://www.ijddr.in/drug-development/application-of-spices-in-dentistry-a-literature-review.php?aid=5489 (Accessed on December, 2017)
3. Anusha Rajagopalan. Herbal Products in Oral Hygiene Maintenance –A Review. Journal of Pharmacy 5(1); 48-51
4. Palombo EA. Traditional Medicinal Plant Extracts and Natural Products with Activity against Oral Bacteria: Potential Application in the Prevention and Treatment of Oral Diseases. Available at URL: http://dx.doi.org/10.1093/ecam/nep067 [Accessed on December, 2017].
5. Miller W, The presence of bacterial plaques on the surface of teeth and their significance. Dent Cosmos 1902; 44:425-446
6. Parthasarathy, Villupanoor A., Bhageerathy Chempakam, and T. John Zachariah, eds. Chemistry of spices. Available at URL: https://catbull.com/alamut/Bibliothek/Chemistry_of_Spices.pdf (Accessed on December, 2017).
7. Clove. Available at URL: https://en.wikipedia.org/wiki/Clove[Accessed on December, 2017].
8. Lawless, J. The Illustrated Encyclopaedia of Essential Oils. ISBN 1-85230-661-0.
9. Jesudasan JS, Wahab PU, Sekhar MR. "Effectiveness of 0.2% chlorhexidine gel and a eugenol-based paste on postoperative alveolar osteitis in patients having third molars extracted: a randomised controlled clinical trial". Br J Oral Maxillofac Surg 2015; 53 (9): 826–30.
10. Namrata Dagli, Rushabh Dagli, Rasha Said Mahmoud and Kusai Baroudi. Essential oils, their therapeutic properties, and implication in dentistry: A review. J Int Soc Prev Community Dent. 2015; 5(5): 335–340.
11. Vincent Cobb and Marni Shymkus. Superpowers of Clove for Healthy Teeth and Gums. Available at URL: https://www.akamaibasics.com/blogs/learn-more/the-superpowers-of-clove-for-healthy-teeth-gums
12. Cai L., Wu C.D. Compounds from Syzygium aromaticum possessing growth inhibitory activity against oral pathogens. J Nat Prod 1996; 59(10):987-90.
13. Pachori RR, Antimicrobial Studies of Herbs and Shrubs Against Dental Pathogens. Journal of Empirical Biology2008; 1(1): 10 – 16.
14. Cinnamon. Available at URL: https://en.wikipedia.org/wiki/Cinnamon [Accessed on December, 2017].
15. Mark C. Marchbanks. 15 Herbs and Spices for Added Dental Health. Available at URL: [Accessed on December, 2017].
16. Carrie. Cinnamon Bark- Tooth and Gums Tonic Ingredients.Available at URL: https://www.carrieibbetson.com/2012/01/cinnamon-bark-tooth-and-gums-tonic-ingredients/[Accessed on December, 2017].
17. Chaudhari LKD, Jawale BA, Sharma S, Sharma H, Mounesh Kumar CD, Kulkarni PA. Antimicrobial Activity of Commercially Available Essential Oils against Streptococcus mutans. J Contemp Dent Pract 2012;13(1):71-74
18. Coriander. Available at URL: https://en.wikipedia.org/wiki/Coriander [Accessed on December, 2017].
19. Singh, Ricky, Ajithkrishnan and Kalantharakath, Thanveer and Bafna, Harshaland Patel, Hemal. An In-vivo Evaluation of The Effect of Chewing Coriander Seeds on Salivary pH. Journal of Ahmedabad Dental College and Hospital 2012; 5. 31-34.
20. Silva F, Ferreira S, Queiroz JA, Domingues FC. Coriander (Coriandrumsativum L.) essential oil: its antibacterial activity and mode of action evaluated by flow cytometry. Available at URL: https://www.ncbi.nlm.nih.gov/pubmed/21862758 [Accessed on December, 2017].
21. Turmeric.Available at URL: https://en.wikipedia.org/wiki/Turmeric [Accessed on December, 2017].
22. Nelson, K. M.; Dahlin, J. L.; Bisson, J; (2017). "The Essential Medicinal Chemistry of Curcumin: Miniperspective". Journal of Medicinal Chemistry.2015; 60 (5): 1620–1637.
23. Shweta S. Hugar, Renuka Metgud. Turmeric in Dentistry. Available at URL: http://denteks.in/images/pdf/turmeric-in-dentistry. pdf[Accessed on December, 2017].
24. Lee, K.-H., Kim, B.-S., Keum, K.-S., Yu, H.-H., Kim, Y.-H., Chang, B.-S., Ra, J.-Y., Moon, H.-D., Seo, B.-R., Choi, N.-Y. and You, Y.-O. Essential Oil of Curcuma longa Inhibits Streptococcus mutans Biofilm Formation. Journal Science, 76: H226–H230.
25. Neelakantan, Prasanna,"Effectiveness of curcumin against Enterococcus faecalisbiofilm." Acta Odontologica Scandinavica71(6):1453-7.
26. Cardamom. Available at URL: https://en.wikipedia.org/wiki/Cardamom[Accessed on December, 2017].
27. Aneja, K. R., and Radhika Joshi. "Antimicrobial activity of Amomumsubulatum and Elettaria cardamomum against dental caries causing microorganisms. Available at URL: https://www.researchgate.net/publication/50874100_Antimicrobial_Activity_of_Amomum_subulatum_and_Elettaria_cardamomum_Against_Dental_Caries_Causing_Microorganisms[Accessed on December, 2017].
28. Kubo, Isao, Masaki Himejima, and Hisae Muroi.Antimicrobial activity of flavour components of cardamom Elettaria cardamomum (Zingiberaceae) seed. Journal of agricultural and food chemistry 1991; 39.11: 1984-1986.
29. Devi, P. B.; Ramasubramaniaraja, R. Dental Caries and Medicinal Plants – An Overview. Journal of Pharmacy Research 2009; 2(11): 1669–1675.
30. Priyadarsini K. The chemistry of curcumin: from extraction to therapeutic agent. Molecules 2014; 19 (12): 20091–112.
31. TP Chaturvedi. Uses of turmeric in dentistry: An update. Indian Journal of Dental Research.2009; 20: 107-109.
32. Green Tea. Available at URL: https://en.wikipedia.org/wiki/Green_tea[Accessed on December, 2017].
33. Graham HN. Green tea composition, consumption, and polyphenol chemistry. Prev Med 1992; (3): 334-50.
34. Ramesh R, Rajesh E, Devi G. N, Jimson S. Green Tea in Oral Health – A Review. Biomed Pharmacol Journal. Available at URL: http://dx.doi.org/10.13005/bpj/1016 [Accessed on December, 2017].
35. Rosy Sirisha Neturi, Srinivas R, Vikram Simha B, Sandhya Sree Y, Chandra Shekar T and Siva Kumar. Effects of Green Tea on Streptococcus mutans Counts- A Randomised Control Trail.J Clin Diagn Res. 2014; 8(11):128-130.
36. Steven D. Ehrlich. Green tea. Available at URL:http://www.umm.edu/health/medical/altmed/herb/green-tea[Accessed on December, 2017].
37. Tierra Michael. The Way of Herbs. Available at URL: https://books.google.co.in/books?id=h9RLcUi-XQ8Candprintsec=frontcoveranddq=Tierra+Michael+(1998):+The+Way+of+Herbs.+New+York,+Pocket+Booksandhl=enandsa=Xandved=0ahUKEwjpvJTmmbnXAhVEKY8KHXpID3sQ6AEIMzAD#v=onepageandq=Tierra%20Michael%20(1998)%3A%20The%20Way%20of%20Herbs.%20New%20York%2C%20Pocket%20Booksandf=false[Accessed on December, 2017].
38. SenjiSakanaka, Mujo Kim, Makoto Taniguchiand Takehiko Yamamoto. Antibacterial Substances in Japanese Green Tea Extract against Streptococcus mutans, a Cariogenic Bacterium.
39. Neem Available at URL: https://en.wikipedia.org/wiki/Azadirachta_indica[Accessed on December, 2017].
40. Mohammad A. Alzohairy. Therapeutics Role of Azadirachta indica (Neem) and Their Active Constituents in Diseases Prevention and Treatment. Evid Based Complement Alternat Med. 2016: 7382506.
41. Anirban Chatterjee, Mini Saluja, Nidhi Singh, and Abhishek Kandwal. To evaluate the antigingivitis and antipalque effect of an Azadirachtaindica(neem) mouthrinse on plaque induced gingivitis: A double-blind, randomized, controlled trial. J Indian Soc Periodontol. 2011; 15(4): 398–401.
42. Pierce, Andrea. American Pharmaceutical Association Practical Guide to Natural Medicines. New York: Stonesong Press. P 1999; 338–340.
43. P. E. Petersen, D. Bourgeois, H. Ogawa, S. Estupinan-Day, and C. Ndiaye, “The global burden of oral diseases and risks to oral health,” Bulletin of the World Health Organisation 2005; 83(9), 661–669.
44. B. K. Yeo, L. P. Lim, D. W. Paquette, and R. C. Williams, “Periodontal disease—the emergence of a risk for systemic conditions: pre-term low birth weight,” Annals of the Academy of Medicine Singapore 2005;34 (1),111–116.
45. N. C. J. Packia Lekshmi, N. Sowmia, S. Viveka, J. Raja Brindha and S. Jeeva.The inhibiting effect of Azadirachtaindica againstdental pathogens. Asian Journal of Plant Science and Research 2012; 2 (1):6-10
46. Salvia officinalis Available at URL: https://en.wikipedia.org/wiki/Salvia_officinalis.[Accessed on December, 2017].
47. Mohsen Hamidpour, Rafie Hamidpour, Soheila Hamidpour and Mina Shahlari. Chemistry, Pharmacology, and Medicinal Property of Sage (Salvia) to Prevent and Cure Illnesses such as Obesity, Diabetes, Depression, Dementia, Lupus, Autism, Heart Disease, and Cancer.J Tradit Complement Med. 2012; 4(2): 82–88.
48. Maryam Beheshti-Rouy, Mohadese Azarsina, Loghman Rezaie-Soufi, Mohammad Yousef Alikhani, Ghodratollah Roshanaie and Samira Komaki. The antibacterial effect of sage extract (Salvia officinalis) mouthwash against Streptococcus mutans in dental plaque: a randomized clinical trial. Iran J Microbiol 2015;7(3): 173–177.
49. G. R. Prabu, A. Gnanamani, and S. Sadulla, “Guaijaverin— a plant flavonoid as potential antiplaque agent against Streptococcus mutans,” Journal of Applied Microbiology 2011; 101(2), 487–495.
50. Thyme Available at URL: https://en.wikipedia.org/wiki/Thyme [Accessed on December, 2017].
51. Constituents and Phytochemicals of Thyme. Available at URL:https://www.mdidea.com/products/proper/proper07004.html [Accessed on December, 2017].
52. SmainChemat, Ratiba Cherfouh, Brahim Y. Meklati and K. Belanteur. Composition and microbial activity of thyme (Thymus algeriensisgenuinus) essential oil. Journal of Essential Oil Research. 2012. 5-11.
53. Trombetta, D., Casteli, F., Sarpietro, M. G., Venuti, V., Cristani, M., Daniele, C., Saija, A., Mazzanti, G. and Bisignano, G. 2005. Mechanisms of antibacterial action of three monoterpenes. Antimicrob. Agents Chemother 2005; 49(6): 2474–2478.
54. Satrani, B., Ghanmi, M., Farah, A., Aafi, A., Fougrach, H., Bourkhiss, B., Bousta, D. and Talbi, M. 2007. Composition chimiqueetactivitéantimicrobienne de l’huileessentielle de Cladanthusmixtus. Bull. Soc. Pharm. Bordeaux 2006; 146: 85–96.
55. Nilima Thosar, Silpi Basak, Rakesh N. Bahadure and MonaliRajurkar. Antimicrobial efficacy of five essential oils against oral pathogens: An in vitro study Eur J Dent 2013; 7(1):71–S77.
56. Peppermint. Available at URL:https://en.wikipedia.org/wiki/Peppermint#Chemical_constituents [Accessed on December, 2017].
57. Eccles R. Menthol and related cooling compounds. J Pharm Pharmacol .1994;46(8):618-630.
58. Behrendt HJ, Germann T, Gillen C, Hatt H, Jostock R. Characterization of the mouse cold-menthol receptor TRPM8 and vanilloid receptor type-1 VR1 using a fluorometric imaging plate reader (FLIPR) assay. Br J Pharmacol 2004; 141(4):737-745.