Research Journal of Pharmacology and Pharmacodynamics

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2321-5836 (Online)
0975-4407 (Print)


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Antidiabetic Potential of Amritarishta Prepared by Traditional and Modern Methods in Alloxan Induced Diabetic rats

Author(s): Preeti Tiwari.

Email(s): preetitiwari198311@yahoo.com

DOI: Not Available

Address: Preeti Tiwari*
Head of Department of Pharmacognosy, Dr. K. N. Modi Institute of Pharmaceutical Education and Research, Modinagar, Uttar Pradesh, India.
*Corresponding Author

Published In:   Volume - 6,      Issue - 3,     Year - 2014

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ABSTRACT:
The objective of the present study was to evaluate the effect of Amritarishta-T and Amritarishta-M prepared by traditional and modern methods respectively and marketed Amritarishta on fasting blood glucose and serum lipid profile in alloxan induced diabetic rats. Oral administration of Amritarishta-T, Amritarishta-M and marketed Amritarishta ( 2 ml/kg p.o.) for 21 days caused a significant decrease in fasting blood glucose (FBG) and showed significant rise in blood glutathione level (GSH) in diabetic rats. Glibenclamide was used as a standard antidiabetic drug (10 mg/kg, p.o). These preparations also caused significant reduction in serum cholesterol, LDL and triglycerides and showed significant rise in serum HDL level in diabetic albino rats. Thus all these preparations were able to maintain the tested parameters near to the normal level significantly.


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Cite this article:
Preeti Tiwari. Antidiabetic Potential of Amritarishta Prepared by Traditional and Modern Methods in Alloxan Induced Diabetic rats. Research Journal of Pharmacology and Pharmacodynamics. 2014; 6(3): 129-134.


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Research Journal of Pharmacology and Pharmacodynamics (RJPPD) (ISSN: print-0975-4407, online- 2321-5836) is an international, peer-reviewed journal, devoted to Pharmacology, Pharmacodynamics and Medical Sciences. The aim of RJPPD is to increase the impact of pharmacological research both in academia and industry, with strong emphasis on quality and originality. RJPPD publishes Original research Articles, Short Communications, Review Articles in all areas of pharmacology, pharmacokinetics and human physiology.

The journal is published quaterly every year in last week of March, June, September and December (i.e. 4 issues in each calendar year).    
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