Author(s): Dipsundar Sahu, Shakti Bhushan, Debajyoti Das, Saroj Kumar Debnath, Laxmidhar Barik, Vandana Meena, Vikas Singh, Amit Kumar Dixit, PVV Prasad

Email(s): drdssahu@gmail.com

DOI: 10.52711/2321-5836.2021.00015   

Address: Dipsundar Sahu1, Shakti Bhushan1, Debajyoti Das1, Saroj Kumar Debnath1, Laxmidhar Barik1, Vandana Meena2, Vikas Singh3 , Amit Kumar Dixit4, PVV Prasad5
1Research Officer (Ayu.), Central Ayurveda Research Institute, Kolkata, CCRAS, Ministry of Ayush, Government of India.
2Ph.D. Scholar, Department of Rasa Shastra & Bhaishajya Kalpana, Faculty of Ayurveda, Institute of Medical Sciences, Banaras Hindu University, Varanasi (U.P.), India.
3Assistant Professor, Department of Roga nidana, Shri Krishna Ayurvedic Medical College and Hospital, Varanasi, UP.
4Assistant Director (Bio. Chem.), Central Ayurveda Research Institute, Kolkata, CCRAS, Ministry of Ayush, Government of India.
5Director, Central Ayurveda Research Institute, Kolkata, CCRAS, Ministry of Ayush, Government of India. *Corresponding Author

Published In:   Volume - 13,      Issue - 2,     Year - 2021


ABSTRACT:
In herbal medicine, there is a substantial amount of variety of plants have been used to treat neurodegenerative disorders including Alzheimer's (AD)as well as other memory-related issues. Dementia is a neurological condition characterised by a progressive loss in emotional and cognitive abilities. Dementia is linked to a number of conditions like inadequate cerebral blood flow, poison toxicity, and other risk factors and conditions mitochondrial dysfunction, oxidative injury, and, in certain cases coexistence with other diseases like Alzheimer's disease (AD), Huntington's disease, Parkinson's syndrome (PD) and Attention Deficit Hyperactivity Disorder (ADHD).Despite the fact that there are well-established semi-synthetic medications for the treatment of AD and AD-related dementia, the majority of them have a number of side effects. As a result, conventional medicine offers a variety of plant-derived lead molecules that may be valuable in future medical studies. In this paper, we look at how ayurvedic plants are used to treat neurodegenerative disease around the world. Plants are also neuroprotective against proinflammatory cytokines including IL-6, IL-1b, TNF-a and it was reported that Antioxidant activity was increased, oxidant levels were reduced, and acetylcholinesterase activity was inhibited in the nervous system by these medicinal plants. We've highlighted the most essential ayurvedic medicinal plants as well as their biochemical effects. As a result, the effects of the above medicinals plants and their active constituents strengthened neurodegenerative conditions, indicating their therapeutic potential in ailments like Alzheimer's disease. and depression that are linked to neuroinflammation and neurotransmitter dysfunction.


Cite this article:
Dipsundar Sahu, Shakti Bhushan, Debajyoti Das, Saroj Kumar Debnath, Laxmidhar Barik, Vandana Meena, Vikas Singh, Amit Kumar Dixit, PVV Prasad. Potential Ayurvedic Herbs for Neurodegenerative Diseases: A review. Research Journal of Pharmacology and Pharmacodynamics. 2021; 13(2):69-4. doi: 10.52711/2321-5836.2021.00015

Cite(Electronic):
Dipsundar Sahu, Shakti Bhushan, Debajyoti Das, Saroj Kumar Debnath, Laxmidhar Barik, Vandana Meena, Vikas Singh, Amit Kumar Dixit, PVV Prasad. Potential Ayurvedic Herbs for Neurodegenerative Diseases: A review. Research Journal of Pharmacology and Pharmacodynamics. 2021; 13(2):69-4. doi: 10.52711/2321-5836.2021.00015   Available on: https://rjppd.org/AbstractView.aspx?PID=2021-13-2-9


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