P Vinoth Kumar, Ch Sudheer Kumar, V Veera Thamarai Selvi, A Amala Bricey.
P. Vinoth Kumar1*, Ch. Sudheer Kumar2, V. Veera Thamarai Selvi1 and A. Amala Bricey3
1Department of Biotechnology, J.J college of Arts and Science, Pudukottai, India.
2School of Life Sciences, Department of Biotechnology, University College of Engineering, JNTU, Kakinada, Andhra Pradesh, India.
3Department of Biotechnology, Bharathidasan University, Trichy, India.
Volume - 3,
Issue - 1,
Year - 2011
The present study was undertaken to examine the inhibitory effect of the Pergularia daemia on cadmium chloride induced hepatoprotective activity in liver. In rats injected with cadmium chloride, the activities of aspartate aminotransferase (AST), alanine aminotransferase (ALT), lactate dehydrogenase (LDH), ? - glutamyl transferase (GGT) was significantly (p < 0.05) increased when compared to those values in control rats. The rats administrated with P.daemia extract and cadmium chloride showed a significantly (p < 0.05) decreased levels of serum AST, ALP, LDH and GGT. This study suggested that P.daemia may be implicated as a hepatoprotective agent for therapeutic purposes.
Cite this article:
P Vinoth Kumar, Ch Sudheer Kumar, V Veera Thamarai Selvi , A Amala Bricey. Hepatoprotective Effect of Pergularia daemia on Cadmium Chloride Induced Toxicity in Rats.Research J. Pharmacology and Pharmacodynamics. 2011; 3(1): 19-21.