Mood Elevating Activity of Plant Chrozophora plicata (Euphorbiaceae)

Kadiri Sunil Kumar; H Padmalatha; Surayya Farheen; Kalakonda Rajesh.

Research Journal of Pharmacology and Pharmacodynamics

ISSN

2321-5836 (Online)
0975-4407 (Print)

Submit Article

Mood Elevating Activity of Plant Chrozophora plicata (Euphorbiaceae)

Author(s): Kadiri Sunil Kumar, H Padmalatha, Surayya Farheen, Kalakonda Rajesh.

Email(s): sunil.cology@gmail.com

DOI: Not Available

Address: Kadiri Sunil Kumar*, H. Padmalatha, Surayya Farheen, Kalakonda Rajesh
Vijaya College of Pharmacy, Munaganoor 501511, Hyderabad, A.P, India
*Corresponding Author

Published In: Volume - 6, Issue - 2, Year - 2014

View HTML

View PDF

ABSTRACT:
The study was designed to investigate the antidepressant effect 70% petroleum ether extract of Chrozophora plicata leaves (600mg/kg) against experimentally induced depression models such as Tail suspension test and Forced swimming test in albino mice. In the tail suspension test, three groups of albino mice, each group containing three animals are used. The control group, test group (Pet. ether extract of Chrozophora plicata 600mg/kg, p.o) and standard (amitriptyline 20mg/kg, p.o) treated animals were suspended by their tail using 75cm long thread for a period of 6 minutes and the total duration of immobility was recorded. In forced swimming test, mice of each group are placed in a beaker (25cm height and 10 cm diameter) filled with water to a depth of 6cms. The duration of immobility was recorded for a period of 10 minutes. It was observed that duration of immobility with test extract treated mice was found to be less (80.6 ±1.51seconds and 245.6± 0.05 seconds) in comparison with the duration of immobility of control treated mice (131.3 ±0.62seconds and 295± 1.47 seconds) in both tail suspension and forced swimming depression models. However the duration of immobilities of test treated mice are not less than the standard amitriptyline (20mg/kg) treated mice. Hence by the decrease in duration of immobility in mice when subjected to depression clearly indicates the presence of antidepressive components in Chrozophora plicata leaf extract. Preliminary phytochemical screening of Chrozophora plicata leaf petroleum ether extract indicates the presence of less polar flavonoids such as flavonones, isoflavones, flavonols and triterpenoids. Therefore the mood elevation activity of crude 70% petroleum ether extract of Chrozophora plicata may be due to less polar flavonoids and triterpenoids.

Keywords:

Cite this article:
Kadiri Sunil Kumar, H Padmalatha, Surayya Farheen, Kalakonda Rajesh. Mood Elevating Activity of Plant Chrozophora plicata (Euphorbiaceae). Research Journal of Pharmacology and Pharmacodynamics. 2014; 6(2): 75-78.

Cite(Electronic):
Kadiri Sunil Kumar, H Padmalatha, Surayya Farheen, Kalakonda Rajesh. Mood Elevating Activity of Plant Chrozophora plicata (Euphorbiaceae). Research Journal of Pharmacology and Pharmacodynamics. 2014; 6(2): 75-78. Available on: https://rjppd.org/AbstractView.aspx?PID=2014-6-2-11

Recomonded Articles:

Pharmacognostical and Pharmacological Review on Tridax procumbens Linn

Author(s): Syed Sagheer Ahmed, Chandra Prakash. K, Saba Tabassum, Noor Salma, Ahalya Devi. K H

DOI: 10.5958/2321-5836.2019.00003.X Access: Open Access Read More

Glossary of Callistemon lanceolatus D.C. – An ornamental plant with Marvellous Properties

Author(s): Shilpa Maria, IJ Kuppast, JH Virupaksha, M Vanajakshi, K Prasad.

DOI: 10.5958/2321-5836.2015.00033.6 Access: Open Access Read More

A Review on Hydnocarpus wightiana

Author(s): Kishan K G, Shekshavali. T, Kuppast I.J, Kishan Kumar MA, Jeevanagouda Patil

DOI: 10.5958/2321-5836.2016.00030.6 Access: Open Access Read More

A Review on Pharmacological Actions of Artocarpus lacoocha Roxb.

Author(s): M. Vanajakshi, J.H. Virupaksha, Shilpa Maria

DOI: 10.5958/2321-5836.2016.00033.1 Access: Open Access Read More

A review on pharmacological activities of Naravelia zeylanica

Author(s): Nikhil P. Varghese, Shekshavali T. , Prathib B., I.J. Kuppast

DOI: 10.5958/2321-5836.2017.00007.6 Access: Open Access Read More

Prosopis juliflora

Author(s): Jeevanagouda Patil, Kuppast I.J, Kishan Kumar M A, Kishan K G

DOI: 10.5958/2321-5836.2016.00032.X Access: Open Access Read More

Celosia argentea: A Review

Author(s): Syed Sulthan Ahamed S N, Shekshavali. T, Syed Shafeeq. R

DOI: 10.5958/2321-5836.2018.00015.0 Access: Open Access Read More

Review Literature: Andrographis paniculata

Author(s): Madhavi Sahu, S. Prakash Rao

DOI: 10.5958/2321-5836.2018.00031.9 Access: Open Access Read More

Experimental studies on the Renal Protective effect of Gokshura (Tribulus terrestris Linn) and Varuna (Crataeva nurvala Buch-Ham)

Author(s): Sudhanshu Kumar Meher, P K Mukherjee, S K Banarjee Chaudhury, Bani Marjit, B PShaw.

DOI: 10.5958/2321-5836.2016.00014.8 Access: Open Access Read More

Effect of Squalene in surgically induced Gastro-oesophageal Reflux Disease on rats

Author(s): Lubna Azmi, Shyam Sundar Gupta, Ila Shukla, Padam Kant, O. P. Sidhu, Ch. V. Rao

DOI: 10.5958/2321-5836.2017.00001.5 Access: Open Access Read More

A Standardized Updated Review Article of Ichnocarpus frutescens Plant

Author(s): Prathib B, Nikhil P Varghese, Virupaksha J. H, Kuppast I. J.

DOI: 10.5958/2321-5836.2017.00006.4 Access: Open Access Read More

Evaluation of hepatoprotective and invitro cytotoxic activity of leaves of Chrozophora plicata Linn

Author(s): Kadiri Sunil Kumar, Avanapu Srinivasa Rao

DOI: 10.5958/2321-5836.2017.00004.0 Access: Open Access Read More

Artocarpus Heterophyllus: Review Study on Potential Activities

Author(s): Mohammed Haleel P M , Rashid K, C. Senthil Kumar

DOI: 10.5958/2321-5836.2018.00005.8 Access: Open Access Read More

Screening of Phytochemicals and Antibacterial Activity of Marine Red Alga Portieria hornemannii (Lyngbye) P. C. Silva

Author(s): Subbiah Murugesan, Sundaresan Bhuvaneswari, U.S. Mahadeva Rao, Vajiravelu Sivamurugan

DOI: 10.5958/2321-5836.2017.00022.2 Access: Open Access Read More

Evaluation of Antidepressant Activity of Ailanthus excelsa roxb. using Mice as Experimental animal.

Author(s): Khushbu Chauhan, Payal Santwani, Lalkrushn Parmar, Roshni Solanki. Subodh Adeshara.

DOI: Not Available Access: Open Access Read More

Anti Diabetic activity and Toxicity Study of Petroleum Ether Extracts of Ixora coccinea Flower in Streptozotocin Induced Diabetic in Albino Rat Model

Author(s): D. Benito Johnson, Faisal N.V, Rashid. K, Mohammed Haleel, V. Venkatanarayanan

DOI: 10.5958/2321-5836.2016.00018.5 Access: Open Access Read More

Diuretic Activity of Fruit Extract of Xanthium strumarium L in Albino Rats

Author(s): MA Halkai, Arun Patil, MD Akhil Ahmed, AK Beknal .

DOI: 10.5958/2321-5836.2016.00004.5 Access: Open Access Read More

Chamomile: A Review

Author(s): Sachin Aglawe, Amol Gayke, Kavita Sharma, Sonali Jadhav, Sanjivani Gore, Bhagyashri Pandit, Sonali Valate, Mayuri Wagh

DOI: 10.5958/2321-5836.2020.00003.8 Access: Open Access Read More

Effect of Chlorophytum borivilianum on Fluoxetine Induced Sexual Dysfunction in Female Rats

Author(s): Neeraj Vyawahare, Virendra Kagathara, Rohini Pujari, Manoj Patil, Imtiyaz Ansari and Amol Bhandare.

DOI: Not Available Access: Open Access Read More

Comparison of the antimicrobial activity of the phyto-constituents obtained from the stem bark and leaf extracts of Phyllanthus emblica L. against different strains of Staphylococcus aureus and Salmonella typhi.

Author(s): Serene Adak, Dipesh Chakraborty, Himangshu S. Maji, Satakshi Basu, Pradip Roy, Sutanuka Mitra, Nabanita Mukherjee, Samarendra Barik, Arunava Goswami

DOI: 10.5958/2321-5836.2018.00009.5 Access: Open Access Read More