Evaluation of Wound Healing Activity of Coscinium fenestratum (Gaertn.) Colebr in Albino Rats

A Thangathirupathi; Bhuvaneswari Santharam.

Research Journal of Pharmacology and Pharmacodynamics

ISSN

2321-5836 (Online)
0975-4407 (Print)

Submit Article

Evaluation of Wound Healing Activity of Coscinium fenestratum (Gaertn.) Colebr in Albino Rats

Author(s): A Thangathirupathi, Bhuvaneswari Santharam.

Email(s): thangathirupathy@rediffmail.com

DOI: Not Available

Address: A. Thangathirupathi1*, and Bhuvaneswari Santharam2
1Department of Pharmacology, S.B. College of Pharmacy, Sivakasi-626130, Tamil Nadu, India
2Department of Biochemistry, S.B. College of Pharmacy, Sivakasi-626130, Tamil Nadu, India
*Corresponding Author

Published In: Volume - 3, Issue - 2, Year - 2011

View HTML

View PDF

ABSTRACT:
The objective of this investigation was to ascertain the scientific basis for the use of the ethanolic extract of Coscinium fenestratum for the treatment of wound. Coscinium fenestratum are used traditionally for the treatment of various diseases. The wound healing activity of Coscinium fenestratum was evaluated for its wound healing potential in two types of experimentally induced in wound models in albino rats excision wound model and incision wound model. Povidone iodine ointment (5% w/w) was used as standard wound healing agent for comparison. In the excision wound model treatment with ethanolic extract ointment at 5% and 10%w/w concentration, enhanced significantly the rate of wound contraction. In the incision wound model the ethanolic extract ointment at 5% and 10%w/w concentration, facilitated the healing process as evidenced by increase in tensile strength. The results suggested that Coscinium fenestratum extract ointment applied possessed significant wound healing activity. Ethanol extract of Coscinium fenestratum was examined in the form of 5% w/w extract and 10% w/w extract in the excision wound extracted on the dorsal side of the experimental animals, the 10% w/w extract ointment showed considerable difference in wound models and the result were compatible to that of the standard drug povidone iodine (5% w/w) in terms of wound contracting ability, epithelisation period and tensile strength.

Keywords:

Cite this article:
A Thangathirupathi, Bhuvaneswari Santharam. Evaluation of Wound Healing Activity of Coscinium fenestratum (Gaertn.) Colebr in Albino Rats. Research J. Pharmacology and Pharmacodynamics. 2011; 3(2): 81-87.

Cite(Electronic):
A Thangathirupathi, Bhuvaneswari Santharam. Evaluation of Wound Healing Activity of Coscinium fenestratum (Gaertn.) Colebr in Albino Rats. Research J. Pharmacology and Pharmacodynamics. 2011; 3(2): 81-87. Available on: https://rjppd.org/AbstractView.aspx?PID=2011-3-2-18

Recomonded Articles:

Pharmacognostical and Pharmacological Review on Tridax procumbens Linn

Author(s): Syed Sagheer Ahmed, Chandra Prakash. K, Saba Tabassum, Noor Salma, Ahalya Devi. K H

DOI: 10.5958/2321-5836.2019.00003.X Access: Open Access Read More

Important Uses of Arka (Calotropis procera Linn) in Indian System of Medicine with Pharmacological Evidence

Author(s): Purnendu Panda, Banamali Das, DS Sahu, SK Meher, BK Das, MM Rao, GChD Naga Lakshmi.

DOI: 10.5958/2321-5836.2015.00011.7 Access: Open Access Read More

A Review on Pharmacological Activities of Abutilon indicum (Atibala)

Author(s): T. Shekshavali, S. Roshan

DOI: 10.5958/2321-5836.2016.00031.8 Access: Open Access Read More

Pharmacological Profile of Terminalia chebula Retz. and Willd. (Haritaki) in Ayurveda with Evidences

Author(s): Sudhanshu Kumar Meher, Purnendu Panda, Banmali Das, G. C. Bhuyan, Dr. K. K. Rath

DOI: 10.5958/2321-5836.2018.00023.X Access: Open Access Read More

Experimental studies on the Renal Protective effect of Gokshura (Tribulus terrestris Linn) and Varuna (Crataeva nurvala Buch-Ham)

Author(s): Sudhanshu Kumar Meher, P K Mukherjee, S K Banarjee Chaudhury, Bani Marjit, B PShaw.

DOI: 10.5958/2321-5836.2016.00014.8 Access: Open Access Read More

Effect of Squalene in surgically induced Gastro-oesophageal Reflux Disease on rats

Author(s): Lubna Azmi, Shyam Sundar Gupta, Ila Shukla, Padam Kant, O. P. Sidhu, Ch. V. Rao

DOI: 10.5958/2321-5836.2017.00001.5 Access: Open Access Read More

Preparation of Novel Biocompatible Honey Hydrogel with Turmaric and Aloe vera.

Author(s): Rohan R. Vakhariya, Rutuja R. Shaha, Archana R. Dhole, C.S Magdum

DOI: 10.5958/2321-5836.2017.00013.1 Access: Open Access Read More

Ethnopharmacology, Phytochemistry and Pharmacology of Adenanthera pavonina L. (Mimosaceae)

Author(s): Kolhe Rohini C., Chaudhari Rajesh Y.

DOI: 10.5958/2321-5836.2019.00025.9 Access: Open Access Read More

Wound Healing Activity of Latex of Euphorbia nivulia Buch.-Ham. in Mice

Author(s): SB Badgujar, RT Mahajan, MZ Chopda.

DOI: Not Available Access: Open Access Read More

Phytochemicals and Pharmacological Activities of Lantana Camara Linn.

Author(s): Patel Jitendra, Qureshi Md Shamim, Kumar G S, Kumar D , Kumar K Ashok.

DOI: Not Available Access: Open Access Read More

Wound Healing and Anti-Bacterial Effects of Cassia auriculata Extract

Author(s): Mathew George, Lincy Joseph.

DOI: Not Available Access: Open Access Read More

Studies on Memory Enhancing Property of Sumenta -A Polymherbal Formulation in Experimentally Induced Alzhiemers Disease in Experimental Animals.

Author(s): Mohibul Hoque, Ramanjaneyulu J, Veeresh Babu. D, Monirul Islam, Narayana Swamy VB.

DOI: 10.5958/2321-5836.2015.00013.0 Access: Open Access Read More

Research Journal of Pharmacology and Pharmacodynamics (RJPPD) is an international, peer-reviewed journal....... Read more >>>

RNI: Not Available
DOI: 10.5958 2321-5836

Journal Policies & Information

Quick Links

Latest Issues

September 2024 (21)

May 2024 (12)

February 2024 (11)

November 2023 (13)

August 2023 (9)

May 2023 (9)

March 2023 (8)

November 2022 (13)

Research Journal of Pharmacology and Pharmacodynamics

Evaluation of Wound Healing Activity of Coscinium fenestratum (Gaertn.) Colebr in Albino Rats

Recomonded Articles:

Pharmacognostical and Pharmacological Review on Tridax procumbens Linn

Important Uses of Arka (Calotropis procera Linn) in Indian System of Medicine with Pharmacological Evidence

A Review on Pharmacological Activities of Abutilon indicum (Atibala)

Pharmacological Profile of Terminalia chebula Retz. and Willd. (Haritaki) in Ayurveda with Evidences

Experimental studies on the Renal Protective effect of Gokshura (Tribulus terrestris Linn) and Varuna (Crataeva nurvala Buch-Ham)

Effect of Squalene in surgically induced Gastro-oesophageal Reflux Disease on rats

Preparation of Novel Biocompatible Honey Hydrogel with Turmaric and Aloe vera.

Ethnopharmacology, Phytochemistry and Pharmacology of Adenanthera pavonina L. (Mimosaceae)

Wound Healing Activity of Latex of Euphorbia nivulia Buch.-Ham. in Mice

Phytochemicals and Pharmacological Activities of Lantana Camara Linn.

Wound Healing and Anti-Bacterial Effects of Cassia auriculata Extract

Studies on Memory Enhancing Property of Sumenta -A Polymherbal Formulation in Experimentally Induced Alzhiemers Disease in Experimental Animals.

Wound Healing Potential of Musa paradisiaca L. (Musaceae) Stem Juice Extract Formulated into an Ointment