Research Journal of Pharmacology and Pharmacodynamics

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2321-5836 (Online)
0975-4407 (Print)


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Potential of Carica papaya against Gentamicin Induced Nephrotoxic Rats

Author(s): Saranya S. and Anuradha R.*

Email(s): Email ID Not Available

DOI: Not Available

Address: PG and Research Department of Biochemistry, Sengamala Thayaar Educational Trust Women’s College, Mannargudi – 614001, Tamil Nadu, India.

Published In:   Volume - 4,      Issue - 1,     Year - 2012

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ABSTRACT:
The present study was desined to evaluate the nephroprotective effect of ethanolic extracts of seeds of Carica papaya against gentamicin induced nephrotoxicity in albino rats. Oral administration of gentamicin (5mg/100g body weight/day) shows the significantly reduction in serum urea, uric acid, creatinine and protein, level were significantly decreased when compared to the control rats. Ethanolic extracts of seeds of Carica papaya administration (40 mg/kg b. wt/day) brought about the significant changes in biochemical parameters. The present work indicates that the Carica papaya extracts has showed their protective role against gentamicin induced nephrotoxicity and its more effective in preventing kidney damage that treating it.


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Not Available   Available on: https://rjppd.org/AbstractView.aspx?PID=2012-4-1-19


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Research Journal of Pharmacology and Pharmacodynamics (RJPPD) (ISSN: print-0975-4407, online- 2321-5836) is an international, peer-reviewed journal, devoted to Pharmacology, Pharmacodynamics and Medical Sciences. The aim of RJPPD is to increase the impact of pharmacological research both in academia and industry, with strong emphasis on quality and originality. RJPPD publishes Original research Articles, Short Communications, Review Articles in all areas of pharmacology, pharmacokinetics and human physiology.

The journal is published quaterly every year in last week of March, June, September and December (i.e. 4 issues in each calendar year).    
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