Dubey R D, Ahmad A R, Paroha S, Sahu P K, Verma S, Daharwal S J, Prasad Reddy S L N, Qureshi M S.
Dubey R. D.1*, Ahmad A. R.1, Paroha S.1, Sahu P. K.1, Verma S.1, Daharwal S. J.1, Prasad Reddy S. L. N.2, and Qureshi M. S.3
1Institute of Pharmacy, RITEE, Chhatauna, Mandir Hasaud, Raipur, Chhattisgarh, India.
2Samskruti College of Pharmacy, Kondapur, Ghatkesar, RR Dist, Hyderabad, Andhra Pradesh, India.
3Anwarul Uloom College of Pharmacy, New Mallepally, Hyderabad, Andhra P
Volume - 2,
Issue - 6,
Year - 2010
Anticancer or antineoplastic drugs are used to treat malignancies. Drug therapy may be used alone or in combination with other treatments such as surgery or radiation therapy. The available anticancer drugs have distinct mechanisms of action which may vary in their effects on different types of normal and cancer cells. A single cure for cancer has proved elusive since there is not a single type of cancer but as many as 100 different types of cancer. In addition, there are very few demonstrable biochemical differences between cancerous cells and normal cells. For this reason the effectiveness of many anticancer drugs is limited by their toxicity to normal rapidly growing cells. A final problem is that cancerous cells which are initially suppressed by a specific drug may develop a resistance to that drug. For this reason cancer chemotherapy may consist of using several drugs in combination for varying lengths of time.
Cite this article:
Dubey R D, Ahmad A R, Paroha S, Sahu P K, Verma S, Daharwal S J, Prasad Reddy S L N, Qureshi M S. A New Profile of Therapeutic Potential and Toxicities of Antineoplastic Drugs. Research J. Pharmacology and Pharmacodynamics. 2010; 2(6): 370-375.