Author(s): Nowshin Nowaz Rumzhum, Md. Mostafizur Rahman, Sadia A. Chowdhury, Most. Nazma Parvin, Mahabub Hasan.

Email(s): nowshin.nowaz@yahoo.com

DOI: Not Available

Address: Nowshin Nowaz Rumzhum*, Md. Mostafizur Rahman, Sadia A. Chowdhury, Most. Nazma Parvin, Mahabub Hasan
Laboratory of Pharmacognosy and Pharmacology, Department of Pharmacy, Stamford University Bangladesh, Dhaka-1217, Bangladesh
*Corresponding Author

Published In:   Volume - 4,      Issue - 2,     Year - 2012


ABSTRACT:
The methanolic extract of the bark of Ficus glomerata Linn. (Family: Moraceae) was evaluated for in vitro antioxidant activity by determination of hydrogen peroxide scavenging activity, total antioxidant capacity, assay of nitric oxide scavenging activity and reducing power test and in vivo antinociceptive effect in acetic acid induced writhing model in Swiss albino mice. The plant extract was also subjected for brine shrimp lethality bio-assay to evaluate its cytotoxic property. The results revealed the presence of pronounced antioxidant property as compared with ascorbic acid used as standard and a dose-dependent (250 and 500 mg/kg) analgesic effect. Investigation also showed that it has strong lelthality (LC50 1.247 µg/ml) against brine shrimp nauplii, Vincristine Sulphate was used as positive control. The antioxidant, antinociceptive and cytotoxic properties observed seem to be in good accordance with the traditional uses of Ficus glomerata.


Cite this article:
Nowshin Nowaz Rumzhum, Md. Mostafizur Rahman, Sadia A. Chowdhury, Most. Nazma Parvin, Mahabub Hasan. Pharmacological Investigation of Methanolic Extract of Ficus glomerata Linn. Bark. Research J. Pharmacology and Pharmacodynamics. 2012; 4(2): 111-115.


Recomonded Articles:

Author(s): Jeevanagouda Patil, Kuppast I.J, Kishan Kumar M A, Kishan K G

DOI: 10.5958/2321-5836.2016.00032.X         Access: Open Access Read More

Author(s): M. Vanajakshi, J.H. Virupaksha, Shilpa Maria

DOI: 10.5958/2321-5836.2016.00033.1         Access: Open Access Read More

Author(s): Purnendu Panda, Banamali Das, DS Sahu, SK Meher, Das, GC Nanda.

DOI: Not Available         Access: Open Access Read More

Author(s): Nikhil P. Varghese, Shekshavali T. , Prathib B., I.J. Kuppast

DOI: 10.5958/2321-5836.2017.00007.6         Access: Open Access Read More

Author(s): Lubna Azmi, Shyam Sundar Gupta, Ila Shukla, Padam Kant, O. P. Sidhu, Ch. V. Rao

DOI: 10.5958/2321-5836.2017.00001.5         Access: Open Access Read More

Author(s): K. Rashid, C. Senthil Kumar, P. M. Mohammed Haleel

DOI: 10.5958/2321-5836.2017.00037.4         Access: Open Access Read More

Author(s): MM Ghaisas, Surbhi Sharma, GP Ganu, RP Limaye.

DOI: Not Available         Access: Open Access Read More

Author(s): Madhavi Sahu, S. Prakash Rao

DOI: 10.5958/2321-5836.2018.00031.9         Access: Closed Access Read More

Author(s): Suneel Kumar A, Venkatarathanamma. V, Naga Saibabu V, Nageswara Rao Tentu, Pavan Kumar Kota, K. Suneel Kumar, A. Vijayalakshmi

DOI: 10.5958/2321-5836.2017.00009.X         Access: Open Access Read More

Author(s): Prathib B, Nikhil P Varghese, Virupaksha J. H, Kuppast I. J.

DOI: 10.5958/2321-5836.2017.00006.4         Access: Open Access Read More

Author(s): Dasari Narendra Prasad

DOI: Not Available         Access: Open Access Read More

Author(s): Ashish Singhai, PK Singour, G Garg, RS Pawar, UK Patil.

DOI: Not Available         Access: Open Access Read More

Author(s): Mohammed Haleel P M , Rashid K, C. Senthil Kumar

DOI: 10.5958/2321-5836.2018.00005.8         Access: Open Access Read More

Author(s): Sudhanshu Kumar Meher, Purnendu Panda, Banmali Das, G. C. Bhuyan, Dr. K. K. Rath

DOI: 10.5958/2321-5836.2018.00023.X         Access: Open Access Read More

Author(s): Sathyaseelan Thennarasan, Subbiah Murugesan, Vajiravelu Sivamurugan

DOI: 10.5958/2321-5836.2017.00011.8         Access: Open Access Read More

Author(s): Srikanth J , Muralidharan P.

DOI: Not Available         Access: Open Access Read More

Author(s): Syed Ibrahim, Mohammed Abrar, Roshan S

DOI: 10.5958/2321-5836.2018.00011.3         Access: Open Access Read More

Author(s): Prakash S. Sukhramani, Piyush M Patel.

DOI: Not Available         Access: Open Access Read More

Research Journal of Pharmacology and Pharmacodynamics (RJPPD) is an international, peer-reviewed journal....... Read more >>>

RNI: Not Available                     
DOI: 10.5958 2321-5836 


Recent Articles




Tags