Research Journal of Pharmacology and Pharmacodynamics

ISSN

2321-5836 (Online)
0975-4407 (Print)


Submit Article

Evaluation of Antidiarrhoeal and Antiulcer Activities of Hydroalcoholic Extract of Luffa aegyptiaca Fruits

Author(s): B Bavaji Naidu, MN Palaksha, K Ravishankar, M Naveen, N Basha.

Email(s): palaksha.mn@gmail.com

DOI: Not Available

Address: B. Bavaji Naidu, M.N. Palaksha*, K. Ravishankar, M. Naveen and N. Basha
Sri Sai Aditya Institute of Pharmaceutical Sciences and Research, Surampalem, E.G.Dist-533437.
*Corresponding Author

Published In:   Volume - 6,      Issue - 4,     Year - 2014

 View HTML        View PDF

ABSTRACT:
The present study investigates the antidiarrhoeal and antiulcer activities of hydroalcoholic fruit extract of Luffa aegyptiaca. The fruits were shade dried and made into a coarse powder which was then subjected to continuous hot extraction in Soxhlet apparatus with hydroalcoholic solvent (ethanol 50% + water 50%) and the residual marc was collected. The extract was used to screen for their antidiarrhoeal and antiulcer activities. The antidiarrhoeal activity was evaluated at two different concentrations viz., 250 mg/kg and 500 mg/kg of the above extract using Castor oil induced diarrhea method in experimental rats. Extract with 500 mg/kg concentration showed significant reduction of induced diarrhoea as compared to the control group animals. But, the antidiarrhoeal activity was found to be less than that of standard drug, Diphenoxylate (5 mg/kg). Anti-ulcer activity was carried out by pylorus ligation method induced gastric ulcer. Ulcer protective action was observed at a dose of 500 mg/kg of Hydroalcoholic fruit extract of Luffa aegyptiaca, which was found to be closer to the standard drug, Famotidine (10 mg/kg).


Keywords:

Cite this article:
B Bavaji Naidu, MN Palaksha, K Ravishankar, M Naveen , N Basha. Evaluation of Antidiarrhoeal and Antiulcer Activities of Hydroalcoholic Extract of Luffa aegyptiaca Fruits. Research Journal of Pharmacology and Pharmacodynamics. 2014; 6(4):184-189.

Cite(Electronic):
B Bavaji Naidu, MN Palaksha, K Ravishankar, M Naveen , N Basha. Evaluation of Antidiarrhoeal and Antiulcer Activities of Hydroalcoholic Extract of Luffa aegyptiaca Fruits. Research Journal of Pharmacology and Pharmacodynamics. 2014; 6(4):184-189.   Available on: https://rjppd.org/AbstractView.aspx?PID=2014-6-4-12


Recomonded Articles:

Evaluation of Anthelmintic Activity of the Chloroform and Aqueous Extracts of leaves of Couroupita guianensis on Pheretima posthuma by Worm Motility Assay Method

Author(s): Praveen Kumar Uppala, Murali Krishna. B , K. Atchuta Kumar , D.J. Vinay Ramji

DOI: 10.5958/2321-5836.2016.00022.7         Access: Open Access Read More

Effect of Squalene in surgically induced Gastro-oesophageal Reflux Disease on rats

Author(s): Lubna Azmi, Shyam Sundar Gupta, Ila Shukla, Padam Kant, O. P. Sidhu, Ch. V. Rao

DOI: 10.5958/2321-5836.2017.00001.5         Access: Open Access Read More

Antiulcer Activity of Colebrookea oppositifolia Sm

Author(s): MM Ghaisas, Surbhi Sharma, GP Ganu, RP Limaye.

DOI: Not Available         Access: Open Access Read More

Comparative Effect of “Pestox” Powdered Insecticide on both Serum Aspartate Aminotransferase and Alanine Aminotransferase of Male and Female Albino Rats

Author(s): Ubani Chibuike Samuel , Joshua Parker Elijah

DOI: Not Available         Access: Open Access Read More

Pharmacological Evaluation of Oxalis corniculata Linn for Anthelmintic Activity

Author(s): Santosh B. Dighe, BS Kuchekar, Sagar B. Wankhede.

DOI: Not Available         Access: Open Access Read More

Effect of Chlorophytum borivilianum on Fluoxetine Induced Sexual Dysfunction in Female Rats

Author(s): Neeraj Vyawahare, Virendra Kagathara, Rohini Pujari, Manoj Patil, Imtiyaz Ansari and Amol Bhandare.

DOI: Not Available         Access: Open Access Read More

Hydro alcoholic extract of Punica granatum for anthelmintic activity

Author(s): Syed Ibrahim, Mohammed Abrar, Roshan S

DOI: 10.5958/2321-5836.2018.00011.3         Access: Open Access Read More

Antidiarrhoeal Activity of Bark Extracts of Caesalpinia sappan. Linn.

Author(s): Rasheed Ahmed, KL Senthilkumar, M Rajkumar.

DOI: Not Available         Access: Open Access Read More

Activity of Ganoderma lucidum on Serum Marker Enzymes in Ochratoxin a treated albino rat models

Author(s): Olukayode Olugbenga Orole, Gerard O. Uyi, Ayofemi F. Gbadeyan

DOI: 10.5958/2321-5836.2016.00027.6         Access: Open Access Read More

Anti-Diarrheal Activity of Methanolic and Aqueous Extracts of Dillenia indica L

Author(s): Yeshwante SB, Juvekar AR, Pimprikar RB, Kakade RT, Tabrej M, Kale MK, Firke SD.

DOI: Not Available         Access: Open Access Read More

Evaluation of Antiulcer Activity of Piper betel Leaves Extract in Rats

Author(s): Neeraj S Vyawahare, Virendra G Kagathara, RG Katedeshmukh, Pushpendra K Sharma, Smeeta M Mohod

DOI: Not Available         Access: Open Access Read More

In- Vitro Anthelmintic Evaluation of Polyherbal Formulation: Krumighattini Tablet

Author(s): Shahin Khan, Ajay Kumar Meena, Ajay Saluja.

DOI: 10.5958/2321-5836.2015.00036.1         Access: Open Access Read More

Antiulcer Effect of Vitamin E with Lansoprazole in Treating Peptic Ulcer in Rats

Author(s): Prasad K, Nitin M, Chetan M, Girish M, Krishna Kumar.

DOI: Not Available         Access: Open Access Read More

Thyroid Disorder: An Overview

Author(s): S. Anandkumar, Jessly Chacko, Theertha C. K, M. Usha

DOI: 10.5958/2321-5836.2020.00001.4         Access: Open Access Read More

Helmintholytic Activity of the Methanolic and Aqueous Extracts of Leaves of Michelia champaca

Author(s): Dama G, Bidkar J, Deore S, Jori M , Joshi P.

DOI: Not Available         Access: Open Access Read More

Phytopharmacological Study of Areca catechu leaf

Author(s): Nishant. M. Patel, H. P. Suryawanshi, S. P. Pawar

DOI: 10.5958/2321-5836.2019.00017.X         Access: Open Access Read More

Helmintholytic Activity of the Methanolic and Aqueous Extract of Seeds of Cleome viscose

Author(s): Matsyagiri Lenkalapally, Sumathi Cheruku, Shravya Koppula, Sindhuja Sandhi, Narayana Mandapu, Gowri Shankar NL.

DOI: Not Available         Access: Open Access Read More

Vector control activity studies on the leaf of Zyziphus mauritiana

Author(s): Sandhya S, Jafferi SAH, Vinod KR, David Banji, Narender Prasad D.

DOI: Not Available         Access: Open Access Read More

Evaluation of anthelmintic activity of Eichhornia crassipes roots

Author(s): BVVS Surya Kiran, Bishnupada Biswal, G Nagarjuna Reddy, LK Kanthal, N Sridhar..

DOI: Not Available         Access: Open Access Read More

Management of Male Infertility by Neutraceutical: A Review

Author(s): SC Shivhare, Arjun O Patidar, KG Malviya, K Venkatesh , Kuldeep Rathod.

DOI: Not Available         Access: Open Access Read More

Research Journal of Pharmacology and Pharmacodynamics (RJPPD) is an international, peer-reviewed journal....... Read more >>>

RNI: Not Available                     
DOI: 10.5958 2321-5836 

Quick Links

Latest Issues

Popular Articles


Recent Articles



Evaluation of Antidibetic Potential of Hydromethanolic Extract of Tridax procubens (Linn) in Mice
Diabetes mellitus A Case Study
Pharmacognostical Study and Phytochemical Evaluation of Pterisvittata L.
Review on WHO
Pharmacological and Therapeutic Potential of Calotropis gigantea and Aerva lanata: A Review
Zika Virus: A Comprehensive Review
The Pharmacological activities of mother of thousand (Kalanchoe pinnata)
Review on Calotropis gigantea use on Diabetic
Implication of Data Obtained from Real Time Stability Studies of Pharmaceutical Preparations
A Project work on Recent approches in the Treatment of Diabetic Nepheropathy
Review on bagworms (Lepidotera: Pyschidae) study in India
A Review on Non-Steroidal Anti-Inflammatory Drugs Induced Kidney Diseases
Therapeutic importance of Asava and Arista (Fermentative Formulation) in Ayurveda: A review
A Study about the pattern of adverse effects of various oncology drugs in a Tertiary Care Hospital of North East India
Drug Interaction of Minoxidil and Himplasia with Oral Anti Diabetic Drug Sitagliptin in Diabetic Rats
Comparative Phyto and Physico-chemical Standardization of Fresh and Different market samples with the Anti-inflammatory Studies of Fruit Parts of Malva sylvestris L.
A Novel Bacterial Culture Media: Fruit Waste Agar
Gullian Barr Syndrome – A Rare Disease Case Report
Incidence of Moxifloxacin serious adverse drug reactions in Pneumococcal infections virus infected patients detected by a Pharmacovigilance program by laboratory signals in a Tertiary hospital in Chhattisgarh (India)
Review on Spinal Muscular Atrophy

Tags


About Journal

Research Journal of Pharmacology and Pharmacodynamics (RJPPD) (ISSN: print-0975-4407, online- 2321-5836) is an international, peer-reviewed journal, devoted to Pharmacology, Pharmacodynamics and Medical Sciences. The aim of RJPPD is to increase the impact of pharmacological research both in academia and industry, with strong emphasis on quality and originality. RJPPD publishes Original research Articles, Short Communications, Review Articles in all areas of pharmacology, pharmacokinetics and human physiology.

The journal is published quaterly every year in last week of March, June, September and December (i.e. 4 issues in each calendar year).    
Read More  

Visitors

Today: 121
Yesterday: 367
Total: 569730