Author(s): Snehal Dilip Kothavale, Guruprasad Vinayak Borgaonkar, S.K. Mohite, S.R. Kane, Savita Satpute

Email(s): snehalkothavale28@gmail.com , guruborgaonkar5997@gmail.com

DOI: 10.52711/2321-5836.2023.00020   

Address: Snehal Dilip Kothavale*, Guruprasad Vinayak Borgaonkar, S.K. Mohite, S.R. Kane, Savita Satpute
Department of Pharmaceutical Chemistry, Rajarambapu College of Pharmacy, Kasegoan, Shivaji University, Kolhapur, Kasegoan 415409, Tal - Walwa, Dist - Sangli, Maharashtra India.
*Corresponding Author

Published In:   Volume - 15,      Issue - 3,     Year - 2023


ABSTRACT:
The Pyrazole nucleus in general and its chemistry has found much more attention during the last few decades because of out-standing biological activities. It acts as Antipyretic, analgesic, anti-inflammatory, kinase inhibitors, and as insecticides. It has good properties as antibacterial, antifungal, and an antiparasitics, as well, considering all those benefits and in continues of our work to synthesize new hetero starting from 1,3-diphenyl-4-carboxaaldehyde, we introduce here in several new pharmacophores, such as pyrimidine, pyramidinethoine and thiazole moieties onto the pyarazole nucleus to obtain compounds with enhanced potency.


Cite this article:
Snehal Dilip Kothavale, Guruprasad Vinayak Borgaonkar, S.K. Mohite, S.R. Kane, Savita Satpute. Research on Synthesis and Pharmacological Evaluation of Subsituated Chalcone deriatives for Antimicrobial and Antifungal activity. Research Journal of Pharmacology and Pharmacodynamics. 2023; 15(3):109-1. doi: 10.52711/2321-5836.2023.00020

Cite(Electronic):
Snehal Dilip Kothavale, Guruprasad Vinayak Borgaonkar, S.K. Mohite, S.R. Kane, Savita Satpute. Research on Synthesis and Pharmacological Evaluation of Subsituated Chalcone deriatives for Antimicrobial and Antifungal activity. Research Journal of Pharmacology and Pharmacodynamics. 2023; 15(3):109-1. doi: 10.52711/2321-5836.2023.00020   Available on: https://rjppd.org/AbstractView.aspx?PID=2023-15-3-3


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3.    Sammes M.P, Kartiki A.R: Adv. Heterocyclic Chem33,38(1883)
4.    Kulkarni S.K, Handbook of Experimental Pharmacology, 3rd Editoon, 127-128(2005)
5.    Ghosh M.N, Fundamental of Experimental Pharmacolgy, Scientific Book Agency Culcutta 155(1951)
6.    Z. Arnold G. Collin, Czech Commun,28, 863 (1963)
7.    S. Selvi, P.T. Permunalorg.Prop.Int.33,194(2001), Chemistry of heterocyclic compound 33,23(1999)
8.    Pelczar, M.J., chan, E.C.S. and Krieg N.R., Microbiology, TATA McGra Whill, 5th edition,3- 17(1993)
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