Author(s): Parag Jain, Anand Surana, Ravindra Pandey, Shiv Shankar Shukla.

Email(s): paragjain1510@gmail.com

DOI: Not Available

Address: Parag Jain*, Anand Surana, Ravindra Pandey, Shiv Shankar Shukla
Columbia Institute of Pharmacy, Raipur, Chhattisgarh, India
*Corresponding Author

Published In:   Volume - 5,      Issue - 1,     Year - 2013


ABSTRACT:
Epilepsy a neurological cramp is a diverse set of neurological disorders characterized by seizures, which results from abnormal, excessive hyper synchronous neuronal activity. Nearly 50 million people have epilepsy worldwide and its 90% probability occurs in developing countries. Epilepsy syndromes are not lifelong some forms are confined to particular stages of childhood. The clinical manifestation consists of a sudden and transitory abnormal phenomenon which may include alterations of consciousness, motor, sensory, autonomic or psychic events, perceived by the patient or an observer. Thus, epileptic seizures are a sign of cerebral dysfunction. Over the last decades, there has been considerable progress in the pharmacotherapy of epilepsy, including the introduction of several new antiepileptic drugs (AEDs) and improved formulations of older drugs and newer technologies of diagnosis, prevention and treatment. Searches for epileptic mechanisms are based upon clinical approaches, and the need to know where the epileptic foci are localized. Such localization depends on both EEG and medical imageries. The latter are based upon various mechanisms, and the uptake of glucose analogs represents one of them. In future better understanding of basic mechanisms which leading to epilepsy, thus allowing to create therapies aimed at the prevention of epilepsy in patients at risk; improved understanding of pharmacoresistance mechanism, allowing to develop drugs for reversal or prevention of resistance; and development of disease-modifying therapies, inhibiting the progression of epilepsy.


Cite this article:
Parag Jain, Anand Surana, Ravindra Pandey, Shiv Shankar Shukla. Epilepsy: A Neurological Cramp. Research J. Pharmacology and Pharmacodynamics. 2013; 5(1): 01-05.


Recomonded Articles:

Author(s): Gharge Deepali, Bavaskar Sunil, Todkar Pavan,Dhabale Pandurang.

DOI: Not Available         Access: Open Access Read More

Author(s): Rohit R. Patil, Mayur A. Chaudhari, Tushar A. Deshmukh

DOI: 10.5958/2321-5836.2018.00016.2         Access: Open Access Read More

Author(s): Manan A Patel, Chetan M Patel, Dipen B Patel, IS Anand , CN Patel.

DOI: Not Available         Access: Open Access Read More

Author(s): Kale Rupali C, Gadgil Swati S, Borole Kanchan D, Wele Asmita A

DOI: 10.5958/2321-5836.2015.00030.0         Access: Open Access Read More

Author(s): Jiban Debnath, Santosh B Dighe, Nachiket S Dighe, Mana Supriya

DOI: Not Available         Access: Open Access Read More

Author(s): Pathan Muzammil Khan, Jha Asha, Pathak Swanand, Jha Rajesh, Khond Sachin, Mujawar Jahir.

DOI: 10.5958/2321-5836.2015.00002.6         Access: Open Access Read More

Author(s): Syed Safiullah Ghori, Md. Shamim Qureshi, Mohammed Safwan Ali Khan, Asma Khanam, Jitendra Patel.

DOI: Not Available         Access: Open Access Read More

Author(s): Emmanuel N Tufon, Ogugua Victor N, Ambeise Umenjoh M, Mbi Alice.

DOI: Not Available         Access: Open Access Read More

Author(s): Parag Jain, Anand Surana, Ravindra Pandey, Shiv Shankar Shukla.

DOI: Not Available         Access: Open Access Read More

Author(s): Chavan G. M., Vasaikar Rupali S., Patil J. K., Hasni Sayyed Hamid, Jain Akash, Vipul H. Jain

DOI: 10.5958/2321-5836.2019.00022.3         Access: Closed Access Read More

Research Journal of Pharmacology and Pharmacodynamics (RJPPD) is an international, peer-reviewed journal....... Read more >>>

RNI: Not Available                     
DOI: 10.5958 2321-5836 


Recent Articles




Tags