Author(s): Jayanth P. C., Prasanna Kumar Kar, M. Niranjan Babu

Email(s): jayanthpharmacy@gmail.com

DOI: 10.5958/2321-5836.2016.00020.3   

Address: Jayanth P. C. *, Prasanna Kumar Kar, M. Niranjan Babu
Department of Pharmacology, Seven Hills College of Pharmacy, Venkataramapuram, Tirupati- 517561.
*Corresponding Author

Published In:   Volume - 8,      Issue - 3,     Year - 2016


ABSTRACT:
The present study was carried to evaluate the nootropic activity potential of krill oil using diazepam (5mg/kg) induced amnesia in mice. Nootropic activity was evaluated using radial arm maze (RAM), Y- maze, Morris water maze were employed to evaluate the activity. The results demonstrated that the percentage of memory increased was comparable with that of standard drug piracetam (20mg/kg). It was observed that there was increase in 45.29% of memory when it was tested in radial arm maze (RAM) and the escape latency was quantified using Morris water maze was gradually decreased from Day 0 to Day 14 i.e. 38.5 ± 0.76 to 13.22 ± 0.31, there was 89.4% of memory increased when the treated animals were tested in Y maze. So by the above results it is concluded that krill oil possess the nootropic activity. So this drug can be used for the various amnesic disorders like Short term memory loss, Alzheimers disease etc.


Cite this article:
Jayanth P. C. , Prasanna Kumar Kar, M. Niranjan Babu. Evaluation of Nootropic activity Potential of Krill Oil in Diazepam Induced Amnesic Mice. Res. J. Pharmacology & Pharmacodynamics.2016; 8(3): 111-114.. doi: 10.5958/2321-5836.2016.00020.3


Recomonded Articles:

Author(s): Kadiri Sunil Kumar, S Mounica, Rajesh Behera, K Vijay Kumar, Y Shanmukh Sai, R Suthakaran

DOI: 10.5958/2321-5836.2016.00013.6         Access: Open Access Read More

Author(s): Jayanth P. C. , Prasanna Kumar Kar, M. Niranjan Babu

DOI: 10.5958/2321-5836.2016.00020.3         Access: Open Access Read More

Author(s): Saraf MN, Sanaye MM, Mengi SA.

DOI: Not Available         Access: Open Access Read More

Author(s): Kadiri Sunil Kumar, R. Suthakaran, Ravindar Bairam

DOI: 10.5958/2321-5836.2018.00028.9         Access: Closed Access Read More

Research Journal of Pharmacology and Pharmacodynamics (RJPPD) is an international, peer-reviewed journal....... Read more >>>

RNI: Not Available                     
DOI: 10.5958 2321-5836 


Recent Articles




Tags