Author(s):
Shubham Kanawade, Chaitanya Vikhe, Vishwas Patare, Harish Pawar
Email(s):
shubhamkanawade96pims@gmail.com
DOI:
10.52711/2321-5836.2024.00029 
Address:
Shubham Kanawade*, Chaitanya Vikhe, Vishwas Patare, Harish Pawar
Department of Pharmaceutics, College of Pharmaceutical Sciences, Pravara Institute of Medical Sciences (DU), Loni, Maharashtra, India.
*Corresponding Author
Published In:
Volume - 16,
Issue - 3,
Year - 2024
ABSTRACT:
Gestational Diabetes Mellitus (GDM) is a significant and growing concern in prenatal care, impacting maternal and neonatal health. This comprehensive review highlights recent advancements in the understanding and management of GDM. The pathophysiology of GDM involves complex interactions between genetic, environmental, and hormonal factors that disrupt glucose homeostasis during pregnancy. Improved screening techniques and diagnostic criteria have led to earlier and more accurate detection. Management strategies have evolved to include not only traditional lifestyle interventions such as diet and exercise but also novel pharmacological treatments and continuous glucose monitoring technologies. The role of multidisciplinary care teams in optimizing pregnancy outcomes is emphasized, ensuring tailored care that addresses the unique needs of each patient. Additionally, the review explores emerging research on the long-term implications of GDM for both mother and child, underscoring the importance of postpartum follow-up and preventive measures. These advancements collectively aim to enhance maternal and fetal outcomes, reduce complications, and provide a framework for future research and clinical practice in GDM.
Cite this article:
Shubham Kanawade, Chaitanya Vikhe, Vishwas Patare, Harish Pawar. Advances in Understanding and Managing Gestational Diabetes Mellitus: A Comprehensive Review. Research Journal of Pharmacology and Pharmacodynamics.2024;16(3):168-4. doi: 10.52711/2321-5836.2024.00029
Cite(Electronic):
Shubham Kanawade, Chaitanya Vikhe, Vishwas Patare, Harish Pawar. Advances in Understanding and Managing Gestational Diabetes Mellitus: A Comprehensive Review. Research Journal of Pharmacology and Pharmacodynamics.2024;16(3):168-4. doi: 10.52711/2321-5836.2024.00029 Available on: https://rjppd.org/AbstractView.aspx?PID=2024-16-3-6
REFERENCES:
1. Modzelewski R, Stefanowicz-Rutkowska MM, Matuszewski W, Bandurska-Stankiewicz EM. Gestational diabetes mellitus—recent literature review. Journal of Clinical Medicine. 2022 Sep 28; 11(19): 5736.
2. Alfadhli EM. Gestational diabetes mellitus. Saudi Medical Journal. 2015; 36(4): 399.
3. Rodriguez Q, Mahdy H. Gestational diabetes.
4. Pillay J, Donovan L, Guitard S, Zakher B, Gates M, Gates A, Vandermeer B, Bougatsos C, Chou R, Hartling L. Screening for gestational diabetes: updated evidence reports and systematic review for the US preventive services task force. JAMA. 2021 Aug 10; 326(6): 539-62.
5. Petry CJ. Gestational diabetes: risk factors and recent advances in its genetics and treatment. British Journal of Nutrition. 2010 Sep;104(6):775-87.
6. Sweeting A, Wong J, Murphy HR, Ross GP. A clinical update on gestational diabetes mellitus. Endocrine Reviews. 2022 Oct 1; 43(5): 76393.
7. Buchanan TA, Xiang AH. Gestational diabetes mellitus. The Journal of Clinical Investigation. 2005 Mar 1; 115(3): 485-91.
8. Petry, E., et al. Placental lactogen and gestational diabetes mellitus. Hormone Molecular Biology and Clinical Investigation, 2020; 45(1): 1-12.
9. Khattab, S., et al. Placental lactogen: A potential target for gestational diabetes mellitus. International Journal of Molecular Sciences. 2022; 23(15): 8575.
10. Aji, A., et al. (2022). Metformin in the preconception period and early pregnancy to prevent gestational diabetes mellitus recurrence: A systematic review and meta-analysis of randomized controlled trials. Journal of Perinatal Medicine, 50(1): 1-12.
11. Qin, J., et al. Gut microbiome and gestational diabetes mellitus: A review of recent advances. Frontiers in Microbiology. 2020; 11: 697663.
12. Koren, O., et al. Gestational diabetes mellitus-associated microbial dysbiosis: A role for pathobionts in metabolic programming? Frontiers in Endocrinology. 2018; 9: 384.
13. Aschuler, J. M., et al. Continuous glucose monitoring for gestational diabetes mellitus: A state-of-the-art review. Diabetes, Metabolism and Research Reviews. 2022; 38(3): e2194.
14. Smets, G., et al. Effect of continuous glucose monitoring on glycemic control and pregnancy outcomes in women with gestational diabetes mellitus: A systematic review and meta-analysis. Diabetes Care. 2022; 45(11): 2446-2453.
15. Yang, Y., et al. Applications of artificial intelligence in gestational diabetes mellitus: A review. Journal of Healthcare Engineering. 2020; 11(1): 1-15.
16. Asadi, N., et al. Artificial intelligence in the management of gestational diabetes mellitus: A systematic review. Journal of Medical Internet Research. 2022; 24(12): e33969.