Research Journal of Pharmacology and Pharmacodynamics

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2321-5836 (Online)
0975-4407 (Print)


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Anthelmintic and Anti-Insect Activities of Memecylon umbellatum Burm Root Extracts

Author(s): SG Killedar, HN More.

Email(s): sureshgk_64@rediffmail.com

DOI: Not Available

Address: SG Killedar* and HN More
Department of Pharmacognosy, Bharati Vidyapeeth College of Pharmacy, Kolhapur, M. S., India.
*Corresponding Author

Published In:   Volume - 2,      Issue - 1,     Year - 2010

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ABSTRACT:
Different extracts of Memecylon umbellatum Burm root were screened for Anthelmintic and anti-insect activities using Indian earthworms (Pheretima posthuma) and red flour beetle, Tribolium castaneum (Herbst) respectively. The acetone and methanolic extracts exhibited significant (p<0.01) anthelmintic and anti-insect activities compared with the control and other extracts. Albendazole and Piperazine citrate were used as standards for anthelmintic activity while Neem Extract, Celphos (Aluminium phosphide) and citronellal for anti-insect activity. Chloroform, ethyl acetate and aqueous extracts showed weak activities. Acetone root extract showed most promising Anthelmintic activity at 20mg/mi compare to albendazole and insecticidal activity at 10mg concentration comparable to standard celphos (5%). Further investigations are however necessary to explore mechanism(s) of action involved in these pharmacological activities and constituents responsible for both the activities.


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Cite this article:
SG Killedar, HN More. Anthelmintic and Anti-Insect Activities of Memecylon umbellatum Burm Root Extracts. Research J. Pharmacology and Pharmacodynamics. 2010; 2(1):52-56.


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Research Journal of Pharmacology and Pharmacodynamics (RJPPD) (ISSN: print-0975-4407, online- 2321-5836) is an international, peer-reviewed journal, devoted to Pharmacology, Pharmacodynamics and Medical Sciences. The aim of RJPPD is to increase the impact of pharmacological research both in academia and industry, with strong emphasis on quality and originality. RJPPD publishes Original research Articles, Short Communications, Review Articles in all areas of pharmacology, pharmacokinetics and human physiology.

The journal is published quaterly every year in last week of March, June, September and December (i.e. 4 issues in each calendar year).    
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