ISSN
2321-5836 (Online) 0975-4407 (Print)
Author(s): SG Killedar, HN More.
Email(s): sureshgk_64@rediffmail.com
DOI: Not Available
Address: SG Killedar* and HN More Department of Pharmacognosy, Bharati Vidyapeeth College of Pharmacy, Kolhapur, M. S., India. *Corresponding Author
Published In: Volume - 2, Issue - 1, Year - 2010
ABSTRACT: Different extracts of Memecylon umbellatum Burm root were screened for Anthelmintic and anti-insect activities using Indian earthworms (Pheretima posthuma) and red flour beetle, Tribolium castaneum (Herbst) respectively. The acetone and methanolic extracts exhibited significant (p<0.01) anthelmintic and anti-insect activities compared with the control and other extracts. Albendazole and Piperazine citrate were used as standards for anthelmintic activity while Neem Extract, Celphos (Aluminium phosphide) and citronellal for anti-insect activity. Chloroform, ethyl acetate and aqueous extracts showed weak activities. Acetone root extract showed most promising Anthelmintic activity at 20mg/mi compare to albendazole and insecticidal activity at 10mg concentration comparable to standard celphos (5%). Further investigations are however necessary to explore mechanism(s) of action involved in these pharmacological activities and constituents responsible for both the activities.
Cite this article: SG Killedar, HN More. Anthelmintic and Anti-Insect Activities of Memecylon umbellatum Burm Root Extracts. Research J. Pharmacology and Pharmacodynamics. 2010; 2(1):52-56.
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