A Systematic Review on Phytochemical Constituents and Pharmacological activities Ricinus communis plant

Megharaj K. V.; Veera Shekhar T; M. R Pavithra; Mohammed Sarfaraz M.

doi:10.52711/2321-5836.2025.00008

Research Journal of Pharmacology and Pharmacodynamics

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2321-5836 (Online)
0975-4407 (Print)

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A Systematic Review on Phytochemical Constituents and Pharmacological activities Ricinus communis plant

Author(s): Megharaj K. V., Veera Shekhar T, M. R Pavithra, Mohammed Sarfaraz M.

Email(s): megharajkv98@gmail.com

DOI: 10.52711/2321-5836.2025.00008

Address: Megharaj K. V.*, Veera Shekhar T, M. R Pavithra, Mohammed Sarfaraz M.
Department of Pharmacology, National College of Pharmacy, Balraj Urs Road, Shivamogga. 577201, Karnataka.
*Corresponding Author

Published In: Volume - 17, Issue - 1, Year - 2025

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ABSTRACT:
Medicinal plants are essential to maintaining human health. There are 7,500 species and over 300 genera in the broad family Euphorbiaceae. The castor bean plant, Ricinus communis L., is highly valued for its traditional and medical uses in promoting a community free of illness. Ricinus communis L. "Castor plant" belongs to the family Euphorbiaceae. The other names such as "wonder tree" or "Palma Christi. It is a small tree which is found all over the India. All parts of plant are important viz. bark, leaves, flowers, seed, oil etc. Oil of this plant is extensively used in Ayurveda, Unani, Homeopathic and Allopathic system of medicines as cathartic. Researchers are concluded that Ricinus communis is the medicinal properties to treat so many diseases like anti-diabetic, anticancer, anti-inflammatory, analgesic, antiulcer, anti-asthmatic, anthelmintic, hepatoprotective, anti-fertility, laxative and uterine contracting, skin disease, bone regeneration, ophthalmic property, wound healing activity, molluscicidal and larvicidal activity, antihistaminic activity, antidandruff activity, anti-oxidant activity, antimicrobial activity, antifungal activity, antinociceptive, immunomodulatory activity, cytotoxic activity, insecticidal activity, hypolipidemic activity and many other medicinal properties. Plant possesses significant pharmacological activities due to the important phytochemical constituents like flavonoids, saponins, glycosides, alkaloids and steroids etc. The aim of this paper is to explain the details of phytochemical and pharmacological properties of Ricinus communis for the future research work.

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Cite this article:
Megharaj K. V., Veera Shekhar T, M. R Pavithra, Mohammed Sarfaraz M. A Systematic Review on Phytochemical Constituents and Pharmacological activities Ricinus communis plant. Research Journal of Pharmacology and Pharmacodynamics. 2025; 17(1):47-1. doi: 10.52711/2321-5836.2025.00008

Cite(Electronic):
Megharaj K. V., Veera Shekhar T, M. R Pavithra, Mohammed Sarfaraz M. A Systematic Review on Phytochemical Constituents and Pharmacological activities Ricinus communis plant. Research Journal of Pharmacology and Pharmacodynamics. 2025; 17(1):47-1. doi: 10.52711/2321-5836.2025.00008 Available on: https://rjppd.org/AbstractView.aspx?PID=2025-17-1-8

REFERENCES:
1.    Kamboj VP. Herbal Medicine. J Cur Sc. 2000; 78(1): 35-39.
2.    Ullah N, Muhammad Z, Khan F. A and Khan S. A review on general introduction to medicinal plants, its phytochemicals and role of heavy metal and inorganic constituents. Life Sci J. 2014; 11(7): 520-27.
3.    Scarpa A, Guerci A. Various uses of the castor oil plant (Ricinus communis L.) a review.     J Ethnopharmacol. 1982; 5(2): 117-137.
4.    M. Abbas, A. Ali, M. Arshad et al. Mutagenicity, cytotoxic and antioxidant activities of Ricinus communis different parts. Chemistry Central Journal. 2018; 12(1): 1–9.
5.    Ogunniyi DS. Castor oil: A vital industrial raw material. Bioresour Technol. 2006; 97(9): 1086-1091.
6.    Hausmann A, Müller GC. The biblical worms on Jonah's Ricinus were Olepa schleini larvae (Lepidoptera, Arctiidae). Mitt Münch Ent Ges. 2006; 95: 5–99.
7.    Chan AP, Crabtree J, Zhao Q, Lorenzi H, Orvis J, Puiu D, et al. Draft genome sequence of the oilseed species Ricinus communis. Nat Biotechnol. 2010; 28(9): 951-956.
8.    Berman, P., Nizri, S., Wiesman, Z. Castor oil biodiesel and its blends as alternative fuel. Biomass Bioenerg. 2011; 35: 2861-2866.
9.    Alugah CI, Ibraheem O. Whole plant screenings for flavonoids and tannins contents     in castor plant (Ricinus communis L.) and evaluation of their biological activities. Int J Herbal Med. 2014; 2(2): 68-76.
10.    Vermeer CP, Nastold P, Jetter R. Homologous very-long-chain 1,3-alkanediols and 3-hydroxyaldehydes in leaf cuticular waxes of Ricinus communis L. Phytochem. 2003; 62(3): 433-438.
11.    Jeyam M, Arangaraj M, Ravikumar P, Shalini G. Computational analysis of phytocompounds with 1,3-D-glucan synthase for antidermatophytic activity. Sci Rep. 2014; 6: 24027.
12.    Rana M, Dhamija H, Prashar B, Sharma S. Ricinus communis L. A review. Int J Pharm Tech Res. 2012;4(4):1706-11.
13.    Chouhan HS. Swarmakar G and Jogpal B. Medicinal properties of Ricinus communis: a review. Int J Phum Sci and Res. 2921: 1217): 3632-42.
14.    Yoganarasimha SN. Textbook of Medicinal Plant of India. Interline Publishing Pvt. Ltd. Bangalore. Vol (1):130.
15.    Sivarajan V.V., and Balachandran, Ayurvedic Drugs and Their Plant Source; Oxford and IBH Publishing Co Pvt Ltd, New Delhi, 149(1994).
16.    The Ayurvedic Pharmacopoeia of India, Ministry of Health and Family Welfare, Department of Health, Govt. of India, Part 1, 1st ed., Vol (1), 34(1989).
17.    http://publish.plantnet-                    project.org/project/plantinvasivekruger/collection/collection/synthese/details/RIICO
18.    Sarfaraz Khan Marwat et al. Pak J Pharm Sci. 2017 Sep; 30(5): 1815-1827.
19.    Shokeen P, Anand P, Murali YK, Tandon V. Antidiabetic activity of 50% ethanolic extract of Ricinus communis and its purified fractions. Food Chem Toxicol. 2008; 46(11): 3458-3466.
20.    Matthew OO, Olusola L, Matthew OA. Preliminary study of hypoglycaemic and hypolipidemic activity of aqueous root extract of Ricinus communis in alloxan-induced diabetic rats. J Phys Pharm Adv. 2012; 2(10): 354-359.
21.    Prakash E, Gupta DK. In vitro study of extracts of Ricinus communis Linn on human cancer cell lines. J Med Sci Pub Health. 2014; 2(1): 15 20.
22.    Shah TI, Sharma E, Shah GA. Inhibitory property of aqueous extract of Ricinus communis leaves on proliferation of melanoma treated against A375 cell lines. World J Pharma Sci. 2015; 3(4): 758-761.
23.    Ilavarasan R, Mallika M, Venkataraman S. Anti-inflammatory and free radical scavenging activity of Ricinus communis root extract. J Ethnopharmacol. 2006; 103: 478-80.
24.    Adriana Cristina Valderramas; Sérgio Henrique Pereira Moura; Maira Couto, Silvana Pasetto; Gilberto Orivaldo Chierice; Sergio Augusto Catanzaro Guimarães5; Ana Claudia Bensuaski de Paula Zurron; Anti-inflammatory activity of Ricinus communis derived polymer; Braz J Oral Sci. 2008; 7(27).
25.    Kore K.J., Shete R.V.., Kabra M.P., Rachhadiya R.M. Evaluation of analgesic activity of castor oil in experimental animals. International Journal of Universal Pharmacy and Life Sciences. 2011; 1(2).
26.    Rachhadiya RM, Kabra MP and Shete RV. Evaluation of antiulcer activity of castor oil in rats. International Journal of Research in Ayurveda & Pharmacy. 2011; 2(4): 1349-1353.
27.    Dnyaneshwar J Taur et al. Asian Pacific Journal of Tropical Biomedicine. 2011: S13-S16.
28.    Rana M, Kumar H, Parashar B. In vitro anthelmintic activity of bark of Ricinus communis Linn. J Chem Pharma Res. 2013; 5(6): 40-42.
29.    Tunaru S, Althoff TF, Nusing RM, Diener M, Offermanns S. Castor oil induces laxation and uterus contraction via ricinoleic acid activating prostaglandin EP3 receptors. Proc Natl Acad Sci USA. 2012; 109(23): 9179-9184.
30.    Sibi G, Kaur G, Devi G, Kumar K.R.R and Mallesha H. Anti-dandruff activity of Ricinus communis Linn. leaf extracts. Int J Curr Pharm Res. 2012; 4(3): 74-76.
31.    PA Botham. In Vitro Toxicol. 2003; 18: 227-230.