Author(s): Patil SM, Maske AP Sapkale GN, Kure AB.

Email(s): akhilxl@yahoo.com

DOI: Not Available

Address: Patil SM*, Maske AP Sapkale GN and Kure AB
ASPM’s. K. T.Patil Collage of Pharmacy Osmanabad- 413 501(MS) INDIA.
*Corresponding Author

Published In:   Volume - 2,      Issue - 2,     Year - 2010


ABSTRACT:
A Vaccine is a preparation, which is used to stimulate immune system, improves immunity to a particular disease. Vaccine can be prophylactic or therapeutic. Most vaccine registered for use is designed to prevent or control acute human infections. The conventional approaches to vaccine Research and Development are as Isolation and Characterization of disease causing organism, to discover methods to effectively immunize and protect susceptible host and to develop assay to measure immune response and identity immune correlates of protection, Manufacturing and Preclinical development, Clinical and Field testing in humans. New approaches to vaccine development are as use of anti-idiotype antibody preparation to mimic B-cells epitops, Synthesis of oligo or polypeptides that reflect naturally occurring a sequence of protein of pathogen. rDNA Transfection of cells with inserted DNA/CDNA into genome of other viruses and bacteria. New prophylactic and therapeutic vaccines will prevent and potentially cure disease. New delivery systems for human vaccines are being developed to enhance cellular and Mucosal immunity, as well as ease of use, advances in current vaccines such as conjugated pneumococcal vaccines for adults, nasal spray vaccines for Influenza and adult a cellular pertussis vaccine will provide an efficient way to of longlasting protective immunity. There is as of today no TH1 adjuvant efficient in humans. Such adjutants are needed to develop powerful therapeutic vaccines against cancer or chronic infectious diseases. New vaccine delivery technology will provide easier delivery routs such as transcutaneous, depot, nasal, and oral delivery without compromising efficacy.


Cite this article:
Patil SM, Maske AP Sapkale GN, Kure AB. Unique Approaches to Vaccine Development Formulation and Delivery. Research J. Pharmacology and Pharmacodynamics. 2010; 2(2):99-102 .


Recomonded Articles:

Author(s): M. Vanajakshi, J.H. Virupaksha, Shilpa Maria

DOI: 10.5958/2321-5836.2016.00033.1         Access: Open Access Read More

Author(s): Jhakeshwar Prasad, Ashish Kumar Netam, Mahendra Kumar Sahu, Trilochan Satapathy

DOI: 10.5958/2321-5836.2017.00027.1         Access: Open Access Read More

Author(s): Mohammed Haleel P M , Rashid K, C. Senthil Kumar

DOI: 10.5958/2321-5836.2018.00005.8         Access: Open Access Read More

Author(s): Salunke Pradnya Balasaheb, Patil Sandeep Balvant, Kadam A.T.

DOI: 10.5958/2321-5836.2017.00021.0         Access: Open Access Read More

Author(s): Vandna Dewangan, Himanshu Pandey

DOI: 10.5958/2321-5836.2017.00039.8         Access: Open Access Read More

Author(s): Sathyaseelan Thennarasan, Subbiah Murugesan, Vajiravelu Sivamurugan

DOI: 10.5958/2321-5836.2017.00011.8         Access: Open Access Read More

Author(s): Kuchake VG, Patil PH, Mahajan HS, Ingle PV, Surana SJ, Thakare MM, S Sudharshini.

DOI: Not Available         Access: Open Access Read More

Author(s): Suryawanshi CP, Patil VR, Chaudhari RY, Kale MK, Firake SD, Pimprikar RB, Patil MD, Yeshwante SB, Saindanem DS.

DOI: Not Available         Access: Open Access Read More

Author(s): Kanase KG, Shinde NV, Bharti DK, Undale VR, Bhosale AV.

DOI: Not Available         Access: Open Access Read More

Author(s): Pushpa A. Karale, Mahesh A. Karale, Mokshada C. Utikar

DOI: 10.5958/2321-5836.2018.00006.X         Access: Open Access Read More

Author(s): AS Rajput, SK Dwivedi, Manish Goyal.

DOI: 10.5958/2321-5836.2016.00003.3         Access: Open Access Read More

Author(s): C. H. Praveena, K. Pramod, K. C. Ajithkumar

DOI: 10.5958/2321-5836.2016.00026.4         Access: Open Access Read More

Author(s): Shoaib Ahmad

DOI: 10.5958/2321-5836.2017.00017.9         Access: Open Access Read More

Author(s): Sanat Sharma, Tabish Ahmed, Syed Sajid Ali, Raj Sharma, Devender Sachdev.

DOI: Not Available         Access: Open Access Read More

Author(s): Ashish Kumar Netam, Jhakeshwar Prasad, Trilochan Satapathy

DOI: 10.5958/2321-5836.2018.00004.6         Access: Open Access Read More

Author(s): Archana R Dhole, Vikas R Dhole, Chandrakant S Magdum, Shreenivas Mohite.

DOI: Not Available         Access: Open Access Read More

Research Journal of Pharmacology and Pharmacodynamics (RJPPD) is an international, peer-reviewed journal....... Read more >>>

RNI: Not Available                     
DOI: 10.5958 2321-5836 


Recent Articles




Tags