Author(s): Valli G, Vijayalakshmi R, Vasanthi A, Thanga Thirupathi A.

Email(s): mrs.valliravichandran@gmail.com

DOI: Not Available

Address: Valli G.1, Vijayalakshmi R.1, Vasanthi A.1 and Thanga Thirupathi A.2
1Department of Chemistry, SFR College for women, Sivakasi.
2Department of Pharmacology, SB College of Pharmacy, Anaikuttam, Sivakasi.
*Corresponding Author

Published In:   Volume - 3,      Issue - 5,     Year - 2011


ABSTRACT:
Antipyretic and anti-inflammatory activities of different extracts of Odina woodier leaves were studied by observing decrease in rectal temperature and reduction in paw edema using albino rats of both sexes. Animals were divided into ten groups, each consisting of six animals. Group 1 served as control and Group 2 received the standard drug. Group 3-10 received various extracts of Odina woodier leaves. Group 3 received ethanol extracts of 200mg/kg and Group 4 received 400mg/kg. Group 5 and Group 6 received ethyl acetate extracts of 200mg/kg and 400mg/kg respectively. Similarly Group 7 and Group 8 received chloroform extracts of 200mg/kg and 400mg/kg. Group 9 received 200mg/kg and Group 10 received 400mg/kg petroleum ether extracts of Odina woodier leaves. For the determination of antipyretic activity, pyrexia was induced by 20% yeast suspension and for anti-inflammatory activity, inflammation was induced using 1% carageenan suspension. The results showed that all the extracts were found to have both antipyretic and anti-inflammatory activities. Among these four extracts, ethanol extract of 400 mg/kg have shown same antipyretic activity after four hours of drug administration as that of the standard Paracetamol drug which caused the reduction of temperature of 1.03 and 1.02 for the extracts and Paracetamol drug . 400mg/kg of ethyl acetate extract after two hours have shown higher anti-inflammatory activity (40.43%) with a probability < 0.001 than the chosen standard drug diclofenac sodium(39.75%) available as an anti-inflammatory drug in the market.


Cite this article:
Valli G, Vijayalakshmi R, Vasanthi A, Thanga Thirupathi A. Studies of Antipyretic and Anti-Inflammatory Activities of Odina woodier Leaves Extracts. Research J. Pharmacology and Pharmacodynamics. 2011; 3(5): 263-267.


Recomonded Articles:

Author(s): Shameer Pasha, Mohamed Khaleel, Sukhen Som.

DOI: Not Available         Access: Open Access Read More

Author(s): Aswani P. S., Kshirod Kumar Ratha, Dighe Dattatray Pandurang, M. M. Rao, Remya Vijayan

DOI: 10.5958/2321-5836.2018.00008.3         Access: Open Access Read More

Author(s): Jeevanagouda Patil, Kuppast I.J, Kishan Kumar M A, Kishan K G

DOI: 10.5958/2321-5836.2016.00032.X         Access: Open Access Read More

Author(s): Purnendu Panda, Banamali Das, DS Sahu, SK Meher, Das, GC Nanda.

DOI: Not Available         Access: Open Access Read More

Author(s): Purnendu Panda, Banamali Das, DS Sahu, SK Meher, BK Das, MM Rao, GChD Naga Lakshmi.

DOI: 10.5958/2321-5836.2015.00011.7         Access: Open Access Read More

Author(s): T. Shekshavali, S. Roshan

DOI: 10.5958/2321-5836.2016.00031.8         Access: Open Access Read More

Author(s): U. S. Jijith , C. R. Sudhakaran Nair, K. Pramod

DOI: 10.5958/2321-5836.2016.00001.X         Access: Open Access Read More

Author(s): Indranil Chanda, Smriti Rekha Chanda , Sadhan Kr Dutta.

DOI: Not Available         Access: Open Access Read More

Author(s): Kadiri Sunil Kumar, S Mounica, Rajesh Behera, K Vijay Kumar, Y Shanmukh Sai, R Suthakaran

DOI: 10.5958/2321-5836.2016.00013.6         Access: Open Access Read More

Author(s): Sambrekar Sudhir N, Patil PA, Suhas A Patil.

DOI: Not Available         Access: Open Access Read More

Author(s): Sanjib Kumar Das, Anuradha Das, Banamali Das, Purnendu Panda, G. C. Bhuyan, Bipin Bihari Khuntia

DOI: 10.5958/2321-5836.2017.00036.2         Access: Open Access Read More

Author(s): MA Halkai, Arun Patil, MD Akhil Ahmed, AK Beknal .

DOI: 10.5958/2321-5836.2016.00004.5         Access: Open Access Read More

Author(s): Rohit J. Bhor, Harshala Damdhar, Geeta Kokate, Maduri Salve, Swati Andhale

DOI: 10.5958/2321-5836.2016.00025.2         Access: Open Access Read More

Author(s): Suneel Kumar A, Venkatarathanamma. V, Naga Saibabu V, Nageswara Rao Tentu, Pavan Kumar Kota, K. Suneel Kumar, A. Vijayalakshmi

DOI: 10.5958/2321-5836.2017.00009.X         Access: Open Access Read More

Author(s): Prathib B, Nikhil P Varghese, Virupaksha J. H, Kuppast I. J.

DOI: 10.5958/2321-5836.2017.00006.4         Access: Open Access Read More

Author(s): Ajay Kumar Meena, Himanshu Sehgal, MM Rao, P Panda, MM Padhi.

DOI: Not Available         Access: Open Access Read More

Author(s): Thakur Akash U., Popat Ritesh R., Mhaske Shivshankar D., Narkhede Mahesh B., Chinchole Pavan P., Shrikhande Vinayak N

DOI: 10.5958/2321-5836.2017.00019.2         Access: Open Access Read More

Author(s): Jadhav Anil G, Narkhede Sachin B, Patil Mrutyunjay B, Vidyasagar G.

DOI: Not Available         Access: Open Access Read More

Research Journal of Pharmacology and Pharmacodynamics (RJPPD) is an international, peer-reviewed journal....... Read more >>>

RNI: Not Available                     
DOI: 10.5958 2321-5836 


Recent Articles




Tags