Author(s): Nadiminti Satish Reddy, D Santhosha, Vidyasabbani, P Vishwanath Reddy, Ch Venu.

Email(s): satishreddy949@gmail.com

DOI: 10.5958/2321-5836.2015.00037.3   

Address: Nadiminti Satish Reddy*, D. Santhosha, Vidyasabbani, P. Vishwanath Reddy, Ch. Venu
Department of Pharmacology, Vishnu Institute of Pharmaceutical Education and Research, Vishnupur, Narsapur, Medak, Telangana, India.
*Corresponding Author

Published In:   Volume - 7,      Issue - 4,     Year - 2015


ABSTRACT:
The methanolic extract leaves of Cleome gynandra (Family Capparidaceae) was selected to evaluate the antidiarrhoeal activity against castor oil and magnesium sulphate induced diarrhoea in wistar albino rats. The present study was performed at three different doses of 100 mg/kg ,200mg/kg and 400mg/kg methanolic extract of plant .The Methanolic plant extracts shows more effective antidiarrhoeal activity against castor-oil induced diarrhea compared to magnesium sulphate induced diarrhoea in a dose dependent manner .From the results we conclude that methanolic leaf extracts of Cleome gynandra had reported antidiarrhoeal activity similar to standard drug loperamaide at dose of 3 mg/kg .


Cite this article:
Nadiminti Satish Reddy, D Santhosha, Vidyasabbani, P Vishwanath Reddy, Ch Venu. Evaluation of Antidiarrhoeal Activity Cleome gynandra Leaf Extracts on Magnesium Sulphate- and Castor Oil-Induced Diarrhoea in Wistar Rats. Research Journal of Pharmacology and Pharmacodynamics. 2015; 7(4): 184-186. doi: 10.5958/2321-5836.2015.00037.3


Recomonded Articles:

Author(s): Yeshwante SB, Juvekar AR, Pimprikar RB, Kakade RT, Tabrej M, Kale MK, Firke SD.

DOI: Not Available         Access: Open Access Read More

Author(s): Rasheed Ahmed, KL Senthilkumar, M Rajkumar.

DOI: Not Available         Access: Open Access Read More

Author(s): Swati Patil, S Prabhu, CI Jolly, S Narayanan.

DOI: Not Available         Access: Open Access Read More

Author(s): Nadiminti Satish Reddy, D Santhosha, Vidyasabbani, P Vishwanath Reddy, Ch Venu.

DOI: 10.5958/2321-5836.2015.00037.3         Access: Open Access Read More

Author(s): Shivakumar SI, Amreen Begum, Syeda Sana, Ansari Firdous

DOI: Not Available         Access: Open Access Read More

Author(s): B Bavaji Naidu, MN Palaksha, K Ravishankar, M Naveen , N Basha.

DOI: Not Available         Access: Open Access Read More

Research Journal of Pharmacology and Pharmacodynamics (RJPPD) is an international, peer-reviewed journal....... Read more >>>

RNI: Not Available                     
DOI: 10.5958 2321-5836 


Recent Articles




Tags