Author(s): Atoussi Ouidad, Chetehouna Sara, Boulaares Islam, Guemari Imane Yousra, Derouiche Samir

Email(s): dersamebio@gmail.com

DOI: 10.5958/2321-5836.2021.00001.X   

Address: Atoussi Ouidad1, Chetehouna Sara1, Boulaares Islam1, Guemari Imane Yousra1, Derouiche Samir1, 2
1Department of Cellular and Molecular Biology, Faculty of Natural and Life Sciences,
University of Echahid Hamma Lakhdar El Oued, El Oued 39000, Algeria.
2Laboratory of Biodiversity and Application of Biotechnology in the Agricultural Field, University of El Oued, El-Oued 39000, Algeria.
*Corresponding Author

Published In:   Volume - 13,      Issue - 1,     Year - 2021


ABSTRACT:
Our study aimed to evaluate the effect of chewing tobacco consumption on lipid profile, blood pressure and hematological biomarkers in chewers men adult. The experimentation is carried out on 22 voluntary individuals were divided into two groups; the first group of healthy individuals (controls) and the second group was tobacco chewers. All the volunteers were subjected to estimate the blood pressure, lipid profile, biochemical and hematological parameters. The finding results showed there are a significant increase (P<0.05) in each of systolic and diastolic blood pressure in chewers when we compare to the control subjects. Also, the level of TC, TG, VLDL-c, LDL-c and Atherogenic index (AI) are highly significant raised (P<0.01). However, the biochemical parameters no changed in chewers group as compared to the control one. Concerning erythrocyte line, there were a significant decrease (P<0.01) of RBC, Hgb, HTC while significant increase of PLT level (p<0.05) in tobacco chewers compared to the controls. But for leukocyte line we didn't notice any significant change in chewers compared to controls. In conclusion the present study revealed that the tobacco consumption in chewing form may be induce sever change in lipid profile which cause the alteration in blood pressure that increased the cardiovascular risk for this population. Additionally, tobacco consumption may be lead to anemia symptoms in its consumers.


Cite this article:
Atoussi Ouidad, Chetehouna Sara, Boulaares Islam, Guemari Imane Yousra, Derouiche Samir. Analysis of Blood Pressure, Lipid Profile and Hematological Biomarkers in men Addicted to Tobacco Chewing. Res. J. Pharmacology and Pharmacodynamics.2021; 13(1):1-4. doi: 10.5958/2321-5836.2021.00001.X

Cite(Electronic):
Atoussi Ouidad, Chetehouna Sara, Boulaares Islam, Guemari Imane Yousra, Derouiche Samir. Analysis of Blood Pressure, Lipid Profile and Hematological Biomarkers in men Addicted to Tobacco Chewing. Res. J. Pharmacology and Pharmacodynamics.2021; 13(1):1-4. doi: 10.5958/2321-5836.2021.00001.X   Available on: https://rjppd.org/AbstractView.aspx?PID=2021-13-1-1


REFERENCES:
1.    Ahmed QR, Gupta N, Goyal S, Ansari S J. Comparative study on lipid profile in tobacco chewers and nontobacco chewers. National Journal of Physiology, Pharmacy and Pharmacology, 2015; 5 (2): 142- 144.
2.    Raut RA, Bagewadi AS. Comparison of Lipid Profile Levels in Tobacco Chewers with and without Leukoplakia- A Hospital Based Study. Ann Med Health Sci Res, 2017; 7: 341-345.
3.    Kwamena SD, Bright OA. Understanding tobacco use andsocioeconomic inequalities among men in Ghana, and Lesotho.Dickson and Ahinkorah Archives of Public Health, 2017; 75 (30): 1-8.
4.    Malenica M, Prnjavorac B, Bego T, Dujic T, Semiz S, Skrbo S, Gusic A, Hadzic A, Causevic A. Effect of Cigarette Smoking on Haematological Parameters in Healthy Population. Med Arch. 2017;71(2):132-136.
5.    Amit DS, Shylaja TV, Asmabi M, Zahoorunissa D. Study of Lipid Profile among Healthy Smokers and Non Smokers. International Journal of Biotechnology and Biochemistry, 2017; 13 (1): 87-94.
6.    DerouicheS, KechridZ. Influence of calcium supplements on zinc status, carbohydrate metabolism and the liver activity of detoxifying glutathione enzymatic system in alloxan induced diabetic rats. J Exp Biol Agr Sci. 2013;1(6): 424- 429.
7.    DerouicheS, CheradidT, GuessoumM. Heavy metals, Oxidative stress and Inflammation in Pathophysiology of Chronic Kidney disease - A Review.Asian Journal of Pharmacy and Technology. 2020; 10(3): 202-206.
8.    Derouiche S, Rezzag-Mohcem OS, Serouti A. The Effect of Herbicide Metribuzin on Environment and Human: A Systematic Review. Pharmaceutical and Biosciences Journal. 2020; 8(4): 10-15.
9.    Neeraj K, Archana S, Neha S, V, Mani T. Comparison of physical fitness between tobacco chewer and non tobacco chewer. Saudi Journal of Sports Medicine, 2015; 15(2): 137-141.
10.    Derouiche S, Abbas K, Djermoune M. Changes in metabolism of Zinc and carbohydrate and testis oxidative stress of diabetic rats fed zinc-over dose diet. Int J Biol Med Res. 2017; 8(3):6041-6045.
11.    Saurabh SP, PatilSN, SomadePM. Comparative study of Pulmonary Function tests in Tobacco chewers and non tobacco chewers. Indian Journal of Basic and Applied Medical Research; 2018: 8 (1), 208- 214.
12.    BakdashA. Shammah (Smokeless Tobacco) and Public Health. Asian Pac J Cancer Prev, 2017; 18 (5): 1183-1190.
13.    Nagamma T, Nirjala LM, Singh PP. Assessment of oxidative damage and lipid profile levels in tobacco chewers with Type 2 diabetes mellitus. Bangladesh Journal of Medical Science, 2019; 18(1):78-82.
14.    Kunnambath R, Catherine S, Gigi T, Jean-Marie F, Somanathan T, Rengaswamy S. Effect of tobacco chewing, tobacco smoking and alcohol on all-cause and cancer mortality: A cohort study from Trivandrum, India. Cancer Epidemiology, 2010; 34: 405-412.
15.    Friedewald WT, Levy RI, Fredrickson DS. Estimation of concentration of lowdensity lipoprotein cholesterol in plasma without use of ultracentrifuge. Clin Chem, 1972; 18: 499-502.
16.    Gomina M, Ngobi GY, Akpona SA. Profil des lipides seriques des sujets adultes beninois consommateurs habituels de tabac. European Scientific Journal, 2013; 9(30): 125- 140.
17.    Janardan VB. Impact of tobacco smoking on coronary risk factor profile. OAI, 2003: 1-5.
18.    Judith JP, Neal LB. Current advances in research in treatment and recovery: Nicotine addiction. Science advances, 2019; 5, 9763.
19.    Hau K, Olsheski K, Katwala P, Wiley R. Oral and Systemic Effects of Smokeless Tobacco from the African, Asian, Latin American, European, and Middle Eastern Regions. Journal of Dental and Oral Health, 2017; 3(1): 1-6.
20.    Benowitz NL, Porchet H, Sheiner L, Jacob P 3rd. Nicotine absorption and cardiovascular effects with smokeless tobacco use: Comparison with cigarettes and nicotine gum. Clin PharmacolTher. 1988; 44(1):23-8.
21.    HaragopalR, ArunaBMK. Effects of Tobacco Chewing on Serum Lipid Profile in South Indian Population. International Journal of Scientific Study, 2016 ;4(4) :9-11.
22.    Elhashimi EH, Haala MG, Zakya AA, Abdalla EA. Effect of Cigarette Smoking on Lipid Profile in Male at Collage of Police and Low Khartoum, Sudan. Asian Journal of Biomedical and Pharmaceutical Sciences, 2013; 3(26):28-31.
23.    Deepa S. Effect of Cigarette Smoking on Serum Lipid Profile in Male Population of Udaipur. Biochem Anal Biochem, 2016; 5(3): 1000283.
24.    Gogania P, Harshwardhan H. Effect of duration of smokeless tobacco (gutka) chewing on lipid profile. International Journal of Basic and Applied Physiology, 2016; 5(1): 146-150.
25.    Derouiche S, Abbas K, Djermoune M. Polysaccharides and ascorbic acid content and the effect of aqueous extract of portulaca oleracea in high-fat diet-induced obesity, dyslipidemia and liver damage in albino wistar rats. Algerian journal of arid environment. 2017; 7(2): 16-26.
26.    Gadpal RR, Deshpande KA, Waghmare MH. A Study of Lipid Profile in Tobacco Chewers and Smokers. Journal of Contemporary Medicine and Dentistry, 2015; 3(2): 39-43.
27.    Ayu A, Ameh EA. Atherogenic indices and smoking habits in cigarette smokers. Environmental Disease, 2018; 3(2): 38-44.
28.    Srinivasa RCH, Emmanuel SY. The Effect of Chronic Tobacco Smoking and Chewing on the Lipid Profile. Journal of Clinical and Diagnostic Research, 2013; 7(1): 31-34.
29.    Kjell A. Smokeless Tobacco and Cardiovascular Disease. Progress in Cardiovascular Diseases, 2003; 45 (5): 383-394.
30.    Salman S, Azmat R, Sangeeta S, Deepak P, Shadab K. Assessment of Cardiovascular Risks of Tobacco Chewers by Comparing it with Normal Human Beings. National Journal of Physiology, Pharmacy and Pharmacology, 2014; 4(1): 76-79.
31.    Gupta BK, Kaushik A, Panwar RB, Chaddha VS, Nayak KC, Singh VB, Gupta R, Raja S. Cardiovascular Risk Factors in Tobacco-chewers: A Controlled Study. The Journal of the Association of Physicians of India, 2007; 55: 27-31.
32.    Saima S, Tasnim F, Nargis F, Ayesha F,Shagufta N. Effect of Nicotine on Hematology, Lipid Profile and Liver Enzymes in Adult Male Mice (Mus Musculus). Advances in Animal and Veterinary Sciences, 2014; 2 (4): 222-225.
33.    Romsha S, Kalpana S. Protective activity of Guduchi and green tea extract on nicotine-induced toxicity in mice. The Pharma Innovation Journal, 2019; 8(1): 650-656.
34.    Derouiche S, Serouti A, Rezzagmohcen OS. Risk of Metribuzin (Triazinone herbicide) on hematological and renal structure and function of pregnancy rabbits. Asian J.Biol. Sci. 2019; 12:192-198.
35.    Fariha M, HazariMAH, KhatoonF, HusnaK, AliSI. Effect of nicotine on platelet function. MedPulse International Journal of Physiology. 2018; 5(2): 13-16.

Recomonded Articles:

Author(s): Syed Sagheer Ahmed, Chandra Prakash. K, Saba Tabassum, Noor Salma, Ahalya Devi. K H

DOI: 10.5958/2321-5836.2019.00003.X         Access: Open Access Read More

Author(s): K. Rashid, C. Senthil Kumar, P. M. Mohammed Haleel

DOI: 10.5958/2321-5836.2017.00037.4         Access: Open Access Read More

Author(s): Madhavi Sahu, S. Prakash Rao

DOI: 10.5958/2321-5836.2018.00031.9         Access: Open Access Read More

Author(s): Satish Narra, Bandenawaz Ramadurg, Saraswathi C D.

DOI: Not Available         Access: Open Access Read More

Author(s): Shoaib Ahmad

DOI: 10.5958/2321-5836.2017.00017.9         Access: Open Access Read More

Author(s): Krishna Murti, Mayank Panchal, Megha Shah, Vijay Lambole.

DOI: Not Available         Access: Open Access Read More

Author(s): VI Zalavadiya, VK Shah, DD Santani, MS Patel, JM Fosi, AK Chaudhary.

DOI: Not Available         Access: Open Access Read More

Author(s): Madhavi T, Soosammajohn, Khambhoja S, Bincy Raj, Amit Kumar.

DOI: Not Available         Access: Open Access Read More

Author(s): S Kavi Priya, V Thamizhiniyan, S Subramanian.

DOI: Not Available         Access: Open Access Read More

Author(s): Maradani Pavani, Bandenawaz Ramadurg, Varshitha C.

DOI: Not Available         Access: Open Access Read More

Author(s): John Masih, Sanjay Kumar, Deepak Kumar

DOI: 10.5958/2321-5836.2018.00013.7         Access: Open Access Read More

Author(s): Preeti Tiwari , Rakesh K Patel.

DOI: Not Available         Access: Open Access Read More

Author(s): Dhruv VK, Singh Sanat, Bansal AK, Shrivastava PK, Khan Q H, Sharma Raj.

DOI: Not Available         Access: Open Access Read More

Author(s): Bharath C L, Bandenawaz Ramadurg.

DOI: Not Available         Access: Open Access Read More

Author(s): S. Acharyya, G.K. Dash, S. Pattnaik , RR Chhetree.

DOI: Not Available         Access: Open Access Read More

Research Journal of Pharmacology and Pharmacodynamics (RJPPD) is an international, peer-reviewed journal....... Read more >>>

RNI: Not Available                     
DOI: 10.5958 2321-5836 


Recent Articles




Tags