Author(s): Patil Divyashree Kantilal, Dhankani Amitkumar R, Dhankani Mansi A, S. P. Pawar

Email(s): divyashree2609@gmail.com , dhankaniamit@gmail.com , laxmipremchandani3@gmail.com , sppawar75@gmail.com

DOI: 10.52711/2321-5836.2024.00015   

Address: Patil Divyashree Kantilal, Dhankani Amitkumar R, Dhankani Mansi A, S. P. Pawar
P.S.G.V.P. Mandal’s College of Pharmacy, Shahada, Maharashtra.
*Corresponding Author E-mail:

Published In:   Volume - 16,      Issue - 2,     Year - 2024


ABSTRACT:
The study explores the causes, evaluation, and treatment of Acne vulgaris, a chronic inflammatory condition caused by Cutibacterium acnes, affecting the pilosebaceous unit. Tinospora cordifolia which is commonly known as gurjo, guduchi or giloy. It is a Menispermaceae herbaceous vine that is only found in the tropics of the Indian subcontinent. The usefulness of these remedies is still debatable despite clinical research, despite being used in Ayurveda to treat a variety of diseases. It has therapeutic qualities such as anti-diabetic, antipyretic, antispasmodic, anti-inflammatory, anti-arthritic, antioxidant, anti-allergic, anti-stress, anti-leprotic, antimalarial, Antimicrobial, hepatoprotective, immunomodulatory, and anti-neoplastic activities, which have been described by scientific research. In this research we have tried to evaluate the formulation of Tinospora cordifolia that shows the Anti-microbial activity for the treatment of Acne vulgaris. We have tested the microbial growth with the help of nutrition broth. We have performed various evaluation parameters of formulation like pH, viscosity, spreadability, physical appearance etc. The results that were obtained were under expectated limits.


Cite this article:
Patil Divyashree Kantilal, Dhankani Amitkumar R, Dhankani Mansi A, S. P. Pawar. Exploring the Potential of Tinospora cordifolia: Formulation and Evaluation of an Innovative Antiacne Cream. Research Journal of Pharmacology and Pharmacodynamics. 2024;16(2):85-9. doi: 10.52711/2321-5836.2024.00015

Cite(Electronic):
Patil Divyashree Kantilal, Dhankani Amitkumar R, Dhankani Mansi A, S. P. Pawar. Exploring the Potential of Tinospora cordifolia: Formulation and Evaluation of an Innovative Antiacne Cream. Research Journal of Pharmacology and Pharmacodynamics. 2024;16(2):85-9. doi: 10.52711/2321-5836.2024.00015   Available on: https://rjppd.org/AbstractView.aspx?PID=2024-16-2-4


REFERENCES:
1.    Suva et al. RRJoP (2014) 1-12 © STM Journals 2014.
2.    Saha S, Ghosh S. Tinospora cordifolia: One plant, many roles. Anc Sci Life. 2012 Apr; 31(4): 151-9. doi: 10.4103/0257-7941.
3.    Upadhyay AK, Kumar K, Kumar A, Mishra HS. Tinospora cordifolia (Willd.) Hook. F. and Thoms. (Guduchi) - Validation of the Ayurvedic Pharmacology Through Experimental and Clinical Studies. Int J Ayurveda Res. 2010 Apr;1(2):112-21. doi: 10.4103/0974-7788.64405.  
4.    J.K. Aronson, Meyler's Side Effects of Drugs (Sixteenth Edition), Elsevier,2016, Pages 494-498, ISBN 9780444537164, https://doi.org/10.1016/B978-0-444-53717-1.01224-5.
5.    William Charles Evans, Daphne Evans, Chapter 19 - Hydrocarbons and derivatives, Editor(s): William Charles Evans, Daphne Evans, Trease and Evans' Pharmacognosy (Sixteenth Edition), W.B. Saunders, 2009, Pages 173-193, ISBN 9780702029332, https://doi.org/10.1016/B978-0-7020-2933-2.00019-8.
6.    https://www.stylecraze.com/articles/triethanolamine-for-skin/#:~:text=Triethanolamine%20is%20also%20said%20to,form%20a%20more%20homogenous%20product.
7.    Investigation of the Functionality of White Soft Paraffin with Regards to Ointments. Phillip John Bentley. University of Leeds. School of Food Science and Nutrition, August 2017.
8.    Churee C, Jiamton S, Udol K, Pratchyapruit W. Bilateral Comparison of Liquid Paraffin and Cream Base on Transepidermal Water Loss among Psoriasis Patients: A Randomized Trial. J Med Assoc Thai. 2018; 101: 1629-33.
9.    Becker LC, Bergfeld WF, Belsito DV, et al. Safety Assessment of Glycerin as Used in Cosmetics. International Journal of Toxicology. 2019; 38(3_suppl): 6S-22S. doi:10.1177/1091581819883820
10.    S. Chaturvedi S. Kulshrestha R. Jangir, A. Vaishnav, D. K. Choudhary (eds.), Microbial Polymers, https://doi.org/10.1007/978-981-16-0045-6_487
11.    M.G. Soni, S.L. Taylor, N.A. Greenberg, G.A. Burdock, Evaluation of the health aspects of methyl paraben: a review.   Food and Chemical Toxicology. 2002; 40(10): 1335-1373   https://doi.org/10.1016/S0278-6915(02)00107-2.
12.    R.R. Cutler. Secondary metabolites, Medicinal and Pharmaceutical Uses, Andrew V. Roberts, Encyclopedia of Rose Science, Elsevier, 2003, 716-726.  ISBN 9780122276200, https://doi.org/10.1016/B0-12-227620-5/00094-X.
13.    Sameeha Khare et al. A Mini Review - Pharmaceutical Creams. Sch Acad J Pharm. 2021 Apr; 10(4): 60-62. doi :10.36347/sajp.2021v10i04.001
14.    Hindawi Publishing Corporation Journal of Pharmaceutics Volume 2016, Article ID 5754349, 10 pages http://dx.doi.org/10.1155/2016/5754349
15.    Dipesh Kumar, Bhaskar Singh, Industrial Crops and Products. 2018; 123; 10-16.   
16.    Chauhan L, Gupta S. Creams: A Review on Classification, Preparation Methods, Evaluation and its Applications. Journal of Drug Delivery and Therapeutics. 2020; 10(5-s): 281-289, http://dx.doi.org/10.22270/jddt.v10i5-s.4430

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