Author(s): Ananda N.V, Shekshavali T, Soundarya M

Email(s): anandaacharyanempe@gmail.com

DOI: 10.52711/2321-5836.2024.00017   

Address: Ananda N.V*, Shekshavali T, Soundarya M
Department of Pharmacology, National College of Pharmacy, Shivamogga - 577201 Karnataka.
*Corresponding Author

Published In:   Volume - 16,      Issue - 2,     Year - 2024


ABSTRACT:
Elaeocarpus serratus tropical flowering tree belong to the family elaeocarpaceae. The fruit of the tree is frequently consumed by people and is also used in folk medicine. The Antidepressant activity of leaf extracts of E. serratus was evaluated using Forced swim test and Tail suspension test. In the present investigation, phytochemical analysis revealed the presence of Flavonoids, Carbohydrates, Proteins, Tannins Saponins, Triterpenoids, Steroids, Glycosides and Alkaloids. The ethanol and aqueous extracts of E. serratus at high dose 400mg/kg showed moderate significance and low dose 200mg/kg showed less significance in antidepressant activity.


Cite this article:
Ananda N.V, Shekshavali T, Soundarya M. Phytochemical Analysis and Antidepressant Activity of Elaeocarpus serratus Extracts in Experimental Models of Depression in Mice. Research Journal of Pharmacology and Pharmacodynamics. 2024;16(2):95-8. doi: 10.52711/2321-5836.2024.00017

Cite(Electronic):
Ananda N.V, Shekshavali T, Soundarya M. Phytochemical Analysis and Antidepressant Activity of Elaeocarpus serratus Extracts in Experimental Models of Depression in Mice. Research Journal of Pharmacology and Pharmacodynamics. 2024;16(2):95-8. doi: 10.52711/2321-5836.2024.00017   Available on: https://rjppd.org/AbstractView.aspx?PID=2024-16-2-6


REFERENCE:
1.    Bikomo EO, Ebuehi O, Magbagbeola O. Antidepressant activity of ethanol leaf extract of Annona muricata L., in Sprague-Dawley rats. Am J Biochem. 2017; 7(1):1-5.
2.    Herrera-Ruiz M, García-Beltrán Y, Mora S, Díaz-Véliz G, Viana GS, Tortoriello J, Ramírez G. Antidepressant and anxiolytic effects of hydroalcoholic extract from Salvia elegans. Journal of Ethnopharmacology. 2006 Aug 11; 107(1):53-8.
3.    Bhattamisra SK, Khanna VK, Agrawal AK, Singh PN, Singh SK. Antidepressant activity of standardised extract of Marsilea minuta Linn. Journal of Ethnopharmacology. 2008 Apr 17; 117(1):51-7.
4.    Murtala AA, Akindele AJ. Anxiolytic-and antidepressant-like activities of hydroethanol leaf extract of Newbouldia laevis (P. Beauv) Seem (Bignoniaceae) in mice. Journal of Ethnopharmacology. 2020 Mar 1; 249:112420.
5.    Goni O, Khan MF, Rahman MM, Hasan MZ, Kader FB, Sazzad N, Sakib MA, Romano B, Haque MA, Capasso R. Pharmacological insights on the antidepressant, anxiolytic and aphrodisiac potentials of Aglaonema hookerianum Schott. Journal of Ethnopharmacology. 2021 Mar 25; 268:113664.
6.    Huang CY, Liu IH, Huang XZ, Chen HJ, Chang ST, Chang ML, Ho YT, Chang HT. Antimelanogenesis effects of leaf extract and phytochemicals from ceylon olive (Elaeocarpus serratus) in zebrafish model. Pharmaceutics. 2021 Jul 10; 13(7):1059.
7.    Dr. Khandelwal K. R. Practical Pharmacognosy. Nirali Prakashan Publication p.149
8.    Porsolt RD, Bertin A, Jalfre MJ. Behavioral despair in mice: a primary screening test for antidepressants. Archives Internationales de Pharmacodynamie et de Therapie. 1977 Oct 1; 229(2): 327-36.
9.    Rosa AO, Kaster MP, Binfaré RW, Morales S, Martín-Aparicio E, Navarro-Rico ML, Martinez A, Medina M, García AG, López MG, Rodrigues AL. Antidepressant-like effect of the novel thiadiazolidinone NP031115 in mice. Progress in Neuro-Psychopharmacology and Biological Psychiatry. 2008 Aug 1; 32(6): 1549-56.

Recomonded Articles:

Author(s): Sudhanshu Kumar Meher, Purnendu Panda, Banmali Das, G. C. Bhuyan, Dr. K. K. Rath

DOI: 10.5958/2321-5836.2018.00023.X         Access: Open Access Read More

Author(s): Khushbu Chauhan, Payal Santwani, Lalkrushn Parmar, Roshni Solanki. Subodh Adeshara.

DOI: Not Available         Access: Open Access Read More

Author(s): Neeraj Vyawahare, Virendra Kagathara, Rohini Pujari, Manoj Patil, Imtiyaz Ansari and Amol Bhandare.

DOI: Not Available         Access: Open Access Read More

Author(s): SB Badgujar, RT Mahajan, MZ Chopda.

DOI: Not Available         Access: Open Access Read More

Author(s): Rohit Gundamaraju Diana Vivian Atigari, DS Helen Sheeba, Ramesh C.

DOI: Not Available         Access: Open Access Read More

Author(s): Kale Rupali C, Gadgil Swati S, Borole Kanchan D, Wele Asmita A

DOI: 10.5958/2321-5836.2015.00030.0         Access: Open Access Read More

Author(s): Praveen Kumar Uppala, Swarna Latha M, Shashidhar Reddy R, G Chakravarthi.

DOI: Not Available         Access: Open Access Read More

Author(s): Manan A Patel, Chetan M Patel, Dipen B Patel, IS Anand , CN Patel.

DOI: Not Available         Access: Open Access Read More

Author(s): Shaik Abdul Saleem, Bathula Lakshmi, J.N. Suresh Kumar

DOI: 10.52711/2321-5836.2021.00014         Access: Open Access Read More

Author(s): N B Sridharamurthy, R Yogananda.

DOI: Not Available         Access: Open Access Read More

Author(s): A Tamil Selvan, R Suresh, N Siva Subramanian, M Rama Devi.

DOI: Not Available         Access: Open Access Read More

Author(s): Amit Roy, Ram Kumar Sahu, Pushpa Prasad.

DOI: Not Available         Access: Open Access Read More

Author(s): Kadiri Sunil Kumar, H Padmalatha, Surayya Farheen, Kalakonda Rajesh.

DOI: Not Available         Access: Open Access Read More

Author(s): Enechi Osmond C, Emmanuel N Tufon, Ogugua Victor N.

DOI: Not Available         Access: Open Access Read More

Author(s): Enechi Osmond C, Emmanuel N Tufon, Ogugua Victor N.

DOI: Not Available         Access: Open Access Read More

Author(s): D Benito Johnson, R Suresh, Prakash Rao Prathima, R Venkatnarayanan , Ashir Ahammad PM.

DOI: Not Available         Access: Open Access Read More


Recent Articles




Tags